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We have received this question to askthechemist@thalesnano.com:

I am thinking of trying a carbonylation reaction using our X-Cube. Any recommendations for reaction conditions, catalyst cartridge and reagents would be greatly appreciated.

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I would recommend you the following reaction conditions as a starting point:
Catalyst: FibreCat 1001 (THS 06131 or THS X1187), this is an immobilized Palladium acetate TPP complex on polyethylene fibres. As an alternative you may try different FibreCat catalyst, or other Pd based catalysts from the C-C Coupling CatCart Pack.
Base: I would recommend to use DBU.
Temperature: 150 °C
Pressure: at least 30 bar
Liquid flow rate: 0.5 ml/min
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