Post Reply 
 
Thread Rating:
  • 0 Votes - 0 Average
  • 1
  • 2
  • 3
  • 4
  • 5
Hydrogenation an aniline to cyclohexylamine
11-17-2014, 12:52 PM (This post was last modified: 11-17-2014 12:52 PM by i.kovacs.)
Post: #1
Hydrogenation an aniline to cyclohexylamine
We have received this question to askthechemist@thalesnano.com:

I would like to use the H-cube to hydrogenate an aniline to cyclohexylamine. However, the only paper that I found uses TFA and PtO2 over a few days. Do you know of any reaction conditions using the H-cube for this particular type of reaction?

I would recommend to use a Ruthenium or Rhodium catalyst (for example 5% Rh/C or 5% Ru/C) and high pressure/temperature (100 °C, 100 bar) for the reduction.
The anilines may stick to the surface of the charcoal, which may decrease the yield of your reaction. This side effect can be reduced if you use alumina supported catalysts instead of the charcoal, however their specific surface and activity are lower than in the case of the carbon supported catalysts.
Find all posts by this user
Quote this message in a reply
12-10-2015, 07:50 AM
Post: #2
RE: Hydrogenation an aniline to cyclohexylamine
thanks
Find all posts by this user
Quote this message in a reply
Post Reply 


Forum Jump: