Publications on ThalesNano instruments and applications

Process Development of a Potent Glucosylceramide Synthase Inhibitor

Cooper, C. G. F.; Lee, E. R.; Silva, R. A.; Bourque, A. J.; Clark, S.; Katti, S.; Nivorozkhin, V.; Process Development of a Potent Glucosylceramide Synthase Inhibitor; Org. Process Res. Dev., Article ASAP
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Continuous Flow Synthesis. A Pharma Perspective; Article

Malet-Sanz, L.; Susanne, F.; Continuous Flow Synthesis. A Pharma Perspective; J. Med. Chem.; Article ASAP
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Synthesis of Amines from Alcohols in a Nonepimerizing One-Pot Sequence – Synthesis of Bioactive Compounds: Cinacalcet and Dexoxadrol

Guerin, C.; Bellosta, V.; Guillamot, G.; Cossy, J.; Synthesis of Amines from Alcohols in a Nonepimerizing One-Pot Sequence – Synthesis of Bioactive Compounds: Cinacalcet and Dexoxadrol; Eur. J. Org. Chem.; Article first published online: 5 APR 2012
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Synthesis of a new family of acylic nucleoside phosphonates, analogues of TPases transition states

Dayde, B.; Benzaria, S.; Pierra, C.; Gosselin, G.; Surleraux, D.; Volle, J.; Pirat, J.; Virieux, D.; Synthesis of a new family of acylic nucleoside phosphonates, analogues of TPases transition states; Org. Biomol. Chem.; 2012, 10, 3448-3454
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Using Continuous Processes to Increase Production

Anderson, N. G.; Using Continuous Processes to Increase Production; Org. Proc. Res. Dev.; Article ASAP
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Diastereoselective 1,3-Dipolar Cycloaddition of Pyrylium Ylides with Chiral Enamides

Tchabanenko, K.; Sloan, C.; Bunetel, Y.; Mullen, P.; Diastereoselective 1,3-Dipolar Cycloaddition of Pyrylium Ylides with Chiral Enamides; Organic and Bioorganic Chemistry; Advance Article
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Stereocontrolled Synthesis of the cis-Hydroxydecalin System: Towards Biologically Active 19-nor-Clerodanes

Mirzayans, P. M.; Pouwer, R. H.; Williams, C. M.; Bernhardt, P. V.; Stereocontrolled Synthesis of the cis-Hydroxydecalin System: Towards Biologically Active 19-nor-Clerodanes; Eur. J. Org. Chem.; 2012; 1633-1638
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Scale-Up of Flow-Assisted Synthesis of C2-Symmetric Chiral PyBox Ligands

Battilocchio, C.; Baumann, M.; Baxendale, I. R.; Biava, M.; Kitching, M. O.; Ley, S. V.; Martin, R. E.; Ohnmacht, S. A.; Tappin, N. D. C.; Scale-Up of Flow-Assisted Synthesis of C2-Symmetric Chiral PyBox Ligands; Synthesis; 2012; 44; 635-647
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Synthesis and biological characterization of sirtuin inhibitors based on the tenovins

McCarthy, A. R.; Pirrie, L.; Hollick, J. J.; Ronseaux, S.; Campbell, J.; Higgins, M.; Staples, O. D.; Tran, F.; Slawin, A. M. Z.; Lain, S.; Westwood, N. J.; Synthesis and biological characterization of sirtuin inhibitors based on the tenovins; Bioorg. Med. Chem.; 2012; 20; 1779-1793
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Reagent-controlled stereoselective synthesis of (±)-gallo- and (±)-epigallo-catechin gallates

Tanaka, H.; Chino, A.; Takahashi, T.; Reagent-controlled stereoselective synthesis of (±)-gallo- and (±)-epigallo-catechin gallates; Tetrahedron Letters; 2012, 53; 2493-2495
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