H-Cube® Mini Plus Application Note

Technical parameters | |
---|---|
Temperature range | RT to 100°C |
Pressure range | ATM to 100 bar |
Modes | No gas or Full Hydrogen |
Hydrogen generation | 20-25 mL/min |
Catalyst amount | 0.1-0.3 g |
Reaction type | Starting material | Product | Conditions* | Catalyst type |
---|---|---|---|---|
Triple bond full reduction | ![]() |
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30 bar, RT | Raney Nickel, 10% Pd/C |
O-debenzylation | ![]() |
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10 bar, 60 °C | 10% Pd/C, 20% Pd(OH)2 |
Nitrile reduction | ![]() |
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50 bar, 60 °C | Raney Nickel, 10% Pd/C |
Selective nitro reduction | ![]() |
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70 bar, 25 °C | 5% Ru/C, RuO2 |
Selective triple to double bond reduction | ![]() |
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10 bar, RT | Lindar catalyst (Pd catalyst on CaCO3, poisoned with Pb) |
Selective double bond reduction | ![]() |
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1 bar, RT | 1% Ir/C, 5% Pt/CaCO3 |
Aldose reduction | ![]() |
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90 bar, 100 °C | Raney Nickel |
Aromatic heterocycle reduction | ![]() |
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70 bar, 70 °C | 10% Pd/C, Raney Nickel |
Aromatic ring reduction | ![]() |
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25 bar, 50 °C | 5% Rh/C, Ru black |
Other heterogeneous catalytic reactions: | ||||
Deuteration (fill the tank with D2O instead of H2O) | ![]() |
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1 bar, RT | Pd/C catalyst (Use non-H2-saturated catalyst!) |
Sonogashira coupling | ![]() |
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100 bar, 100 °C | FibreCat 1000-series |
Suzuki coupling | ![]() |
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20 bar, 100 °C | FibreCat 1000-series |
Kinetic resolution | ![]() |
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1 bar, 40 °C | Immobilized lipase enzyme |