Gas Module Application Notes

The following application notes show the wide range of chemical reactions and synthetic methods which can be implemented with our Gas Module and complimentery systems.

Gas module

1.

Ethanol oxidation with heterogeneous catalysis in flow: a batch to flow conversion

Acetic acid is considered to be an important chemical commodity as both a solvent and Bronsted acid. Being one of the first organic molecules that was synthesized in history (Kolbe, 1845), there are a wide range of procedures for its manufacturing. Despite this fact, industrial scale production now requires more environmentally friendly solutions for its sustainable production.

Heterogeneous catalysis has been found to be a useful alternative method to the current Monsanto process industry currently utilizes. With the combination of ThalesNano’s Phoenix Flow Reactor™ and Gas Module™ a reactor system has been built, which is capable to control high temperature–high pressure triphasic gas-liquid-solid reactions providing a safe and efficient environment for organic chemists.

2.

Gaseous reagent organic chemistry makes easy

The Gas Module works seamlessly with the H-Cube® Pro allowing a further 13 gases to be used at up to 100 bar using the same touch screen intuitive controls. Reactions such as carbonylation or oxidation can now be performed on the H-Cube® Pro at the same high pressure and ease of use, extending the reactor’s chemistry capacity significantly, as it is presented in this application note.

3.

Reaction optimization and real-time analysis using ThalesNano’s platform and Mettler Toledo’s FlowIR™ spectrometer

In this application note we report on the optimization of hydrogenation, oxidation and ring-closing reactions and their real time analysis. Homogeneous and heterogeneous reactions were performed in ThalesNano’s H-Cube® Pro, Gas Module and Phoenix Flow Reactor™ systems, while these reactions were monitored by Mettler Toledo’s FlowIR™ device.