H-Cube® Midi Application Notes

The following application notes show the wide range of chemical reactions and synthetic methods which can be implemented in our H-Cube® continuous flow reactor systems.

H-Cube Midi

1.

How to scale-up hydrogenation reactions using the H-Cube® Midi

The difficulties involved with scaling up reactions from laboratory to process scale are well known. The H-Cube® Midi is designed so that the scale-up of reactions from the milligram scale on H-Cube® to 100s of grams is easy and non-problematic. Using several industrial examples, this application note will describe how reactions were scaled up.

2.

Scale-up of a reductive amination reaction using H-Cube® Midi reactor

The difficulties involved with scaling up reactions from laboratory to process scale are well known. The H-Cube® Midi is designed so that the scale-up of reactions from the milligram scale on H-Cube® to 100s of grams is easy and non-problematic. Using several industrial examples, this application note will describe how reactions were scaled up.

3.

Scaling-up hydrogenation reactions – using the H-Cube® Midi continuous-flow reactor

The difficulties involved in scaling up reactions from laboratory to process scale are well known, especially when dangerous materials are involved. This paper will demonstrate the capability of the H-Cube® Midi to successfully scale-up hydrogenation reactions.