Lipase-catalyzed kinetic resolution using X-Cube™ continuous flow reactor

Enzyme catalyzed biotransformation reactions are now widely used in the chemical industry, most commonly in the synthesis of fine chemicals, but also in the production of drugs, agrochemicals and plastics. One of these enzymes is the lipase which can catalyze hydrolysis and also the esterification of ester chemical bonds in lipid substrates. The main reason for using these enzymes is that they provide enantiomerically pure products during a reaction, often with higher purity than what can be achieved by non-enzyme enantiomer catalysts. Enzymes can be utilized in kinetic resolution, based on the different activity of enantiomers in certain reactions.

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