H-Cube® Midi

Scale-up hydrogenation reactions



  • No need of gas cylinders or other external hydrogen sources
  • Can be used in standard laboratories
  • No need of catalyst filtration or direct catalyst handling
  • Easy catalyst exchange


  • From room temperature to 150 °C
  • From atmospheric pressure to 100 bar
  • Flow rates from 3 to 25 mL/min


  • Higher reaction rates with increased phase mixing
  • Easy-to-use, touch screen controlled
  • Hydrogen introduction can be adjusted and controlled to improve selectivity

How does it work?

  • A continuous flow of substrate is combined with hydrogen, generated in situ from electrolysis of water
  • The hydrogen/substrate mixture can be heated and pressurized up to 150°C (302°F) and 100 bars (1450 psi) respectively
  • The mixture is then passed through a catalyst filled cartridge (MidiCart), where the reaction takes place at elevated flow rate up to 25 mL/min
  • Within minutes, product emerges for fast reduction
  • Reductions varying in scale from 10 g to 500 g can be performed on the same compact reactor

Compatible with Phoenix Flow Reactor™ for wider chemistry space

The Phoenix Flow Reactor™ is a powerful instrument. Its reaction zone can be heated up to 450 °C and is compatible with multiple types and sizes of reaction zones (CatCarts®, MidiCarts™, coils, metal-metal sealed catalyst columns). When connected, the two reactors are controlled separately on their own and it is possible to have the high-throughput flow and hydrogen generation from the H-Cube® Midi with the versatility and high-temperature of the Phoenix Flow Reactor™.

Technical data
Temperature range From room temperature to 150°C
Pressure range From atmospheric pressure to 100 bar
Flow rate 3 – 25 mL/min
Maximum hydrogen production rate 125 mL/min in 100% of hydrogen production
Water reservoir capacity 1000 mL
Water specifications Deionized water with maximum conductivity of 71 nS/cm (min. resistance 14 MΩcm)
System Specifications
Dimensions Height: 43 cm (17”) (including touch screen), Width: 36.5 cm (14.2”), Depth: 54 cm (21.3”)
Weight 23 kg (50 lbs)
Power requirements Mains: 115V to 230V AC, 47 – 63Hz, Automatically adjusted
Power consumption max. 700 VA
Dead volume 12 mL (including inlet and outlet tubes)
Dead volume of MidiCart™ 2.9 mL
Touch-screen Width: 120 mm (4.72″), Height: 89 mm (3.5”)
Tubing Stainless Steel tubing, Outer diameter: 1/16”, Inner diameter: 1 mm
Connection size:
(for inlet and outlet connections)
10 – 32 UNF