Gas Module

Reactions with gases made easy

How does it work?

The Gas Module works seamlessly with the H-Cube Pro™ and with the Phoenix Flow Reactor™ to allow more than 13 gases to be used up to 100 bar pressure, using the same touch screen controls. Reactions, such as carbonylations or oxidations, can now be performed at high pressures, widening the reactor’s chemistry ability significantly:

  • A gas source, typically a gas cylinder, connected to the Gas Module lets out a gas flow that should be in a pressure range between 25 bar and 140 bar
  • The user can select the applicable gas from the list of the Gas Module or set the properties of a new gas
  • The built-in mass flow controller ensures the accurate dosing of the gas, even at high pressure
Features
Versatile 13 gases in one device: compressed air, O2, CO, ethylene, SynGas for hydroformylations, CH4, C2H6, He, H2, N2, N2O, NO, Ar. User can also introduce other gases with well-known thermodynamic properties and compatibility – as an addition, CO2 may be introduced after preheating
Fast Just like with hydrogenation on the H-Cube Pro, reactions with other gases can be complete in less than 10 minutes
Powerful Capability for performing heterogeneous reactions at up to 100 bar
Robust All high quality stainless steel parts
Simple 3-button control or via the touch screen control of the H-Cube Pro™

H-Cube Pro

When the Gas Module is connected to the H-Cube Pro, it allows the introduction of other gas than hydrogen (only one gas at a time), such as carbon monoxide, oxygen or Syngas. The user can choose from further 12 gases to be used at up to 100 bar using the H-Cube Pro’s touch screen control.

Phoenix Flow Reactor

The Phoenix Flow Reactor is a powerful instrument which can be heated up to 450 °C and is compatible with multiple types and sizes of reaction zones (CatCarts, MidiCarts, coils, metal-metal sealed catalyst columns). When one or more Gas Modules are connected with the Phoenix Flow Reactor, it is possible to set up a system to perform catalytic gas reactions with one or more gases. For gas-liquid catalytic reactions in the Phoenix Flow Reactor, the Gas Module, with the aid of a gas-liquid mixer, introduces the gas into the flowing reactant solution moved by an HPLC pump in the form of a flow of microscopic bubbles. Then, this gas-starting material solution will enter the reaction zone. It is also possible to have the widest chemistry space by connecting the H-Cube Pro, the Phoenix Flow Reactor and the Gas Module. All the three devices can be controlled with the H-Cube Pro’s touch screen, resulting in a system capable of handling more than 13 gases (one at a time) with up to two reaction zones: the one from the Phoenix Flow Reactor, which can be heated up to 450 °C, and the CatCart holder from the H-Cube Pro, capable of working between 10 °C and 150 °C, between atmospheric pressure and 100 bar.

Technical Data
Inlet Pressure: Minimum: 25 bar, Maximum 140 bar
Outlet Pressure: Maximum 100 bar
Flow Rates (N2): 0 – 100 NmL/min
MFC Calibrating Gas: Nitrogen
Dimensions: Height: 21 cm (8.27”)

Width: 20 cm (7.87”)

Depth: 30 cm (11.8”)

Weight: ca. 8 kg (17.6 lbs)
Power requirements: 115-230VAC

47-63Hz, 50VA

Fuses: 2×1A-T/230VAC

2×1.6A-T/115VAC

Gas inlet connection: male 1/8” OD (316 SS), 5/64″ ID, 1/64″ wall connection
Gas outlet connection: 1/16” SS line with Swagelok fitting and ferrule

Automation in an extended chemistry space

Fully automated flow chemistry platform, dedicated to automating high pressure and temperature reactions, with or without reagent gases is also available. The system features the H-Cube Pro, the Phoenix Flow Reactor and the Gas Module, combined with an autosampler. The PC controlled automated system is able to inject starting materials into the reaction zone and then to collect product as well. The combined system is one of the most versatile automation systems available and can perform the following:

  • Reactions from 10-450 °C and 1-100 bar (1450 psi)
  • Up to 13 different reagent gases
  • Heterogeneous or homogeneous catalysis

FAQ

You can connect the Gas Module to the H-Cube Pro and to the Phoenix Flow Reactor.
No. For safety reasons, when the Gas Module is connected to the H-Cube Pro, its software automatically blocks the introduction and generation of hydrogen.
No. The Gas Module actually does not generate any gases, it only regulates the amount of gas coming from a cylinder.
Only one cylinder can be used at a time, so the amount of gases depends on the gas type in the cylinder. E.g. gas mixtures such as SynGas can be introduced.
Only gases can be introduced into the Gas Module. To avoid any condensation, you have to make sure the pressure you are using is under the vapor pressure of the gas. Reaction pressure has to be at least 15 bar lower than the pressure of the tank.

The vapor pressure of each gas is given in the below table.

Gas Name

Gas Type

Vapor Pressure

Air

Air

NA

Argon

Ar

NA

Ethylene

C2H4

NA

Ethane

C2H6

543 psi (37 bar)

Methane

CH4

Non condensable

Carbon Monoxide

CO

NA

Carbon Dioxide

CO2

838 psi (58 bar) at 20°C

(preheater is needed to avoid condensation)

Hydrogen

H2

NA

Helium

He

NA

Nitrogen

N2

NA

Nitrous Oxide

N2O

736 psi (50 bar) at 20°C

Nitric Oxide

NO

508 psi (35 bar) at 20°C

Oxygen

O2

NA

Synthesis gas

Syn

NA

H-Cube Mini Plus can work in hydrogen mode ON, for hydrogenations, or hydrogen mode OFF for catalytic reactions that do not require hydrogen, such as C-C coupling reactions. It is not possible to introduce any other type of gasses.

Gas Name

Gas Type

Max flow rate(ml/min)

Max flow rate(mmol/min)

Max flow rate(mg/min)

Air

Air

100

4.46

128.8

Argon

Ar

140

6.23

248.4

Ethylene

C2H4

62

2.77

77.4

Ethane

C2H6

50

2.19

65.7

Methane

CH4

76

3.39

54.2

Carbon monoxide

CO

100

4.44

124.4

Hydrogen

H2

101

4.5

9.1

Helium

He

139

6.19

25

Nitrogen

N2

100

4.46

125

Nitrous Oxide

N2O

76

3.36

147

Nitric Oxide

NO

100

4.46

133.9

Oxygen

O2

99

4.41

141.3

Synthesis Gas

Syn

100

4.46

62.2

The Gas Module does not have a compressor. Please ensure the gas source is able to maintain a pressure above the H-Cube Pro or Phoenix Flow Reactor inlet pressure above the entire duration of the reaction. The reaction pressure is set on H-Cube Pro or in the Pressure Module connected to the Phoenix Flow Reactor between atmospheric pressure and 100 bar. The gas cylinder pressure must be at least 25 bar above the inlet pressure of the reactor.
No. Only dry gases can be introduced into the Gas Module. The use of wet gases is not allowed.
No. H-Cube Pro is equipped with all the software and hardware tools to be connected to the Gas Module and being able to control it.
You will need a gas source (typically a cylinder) with a high-pressure regulator attached. The external fitting should be able to connect to a 1/8 stainless steel tube.
All the gas regulators can be used which parameter’s fit to the specification of the Gas Module, if you order regulator from Linde AG, then please chose the following one: C 200/1 A, 10-200 bar outlet pressure, HiQ code: 3103