H-Cube Systems

On-demand hydrogen and continuous flow technology

Hydrogenation in flow

The first H-Cube system revolutionized laboratory hydrogenation when it was introduced in 2005, earning the prestigious R&D Top 100 award for ThalesNano in the same year. Since then, these reactors have established a new industry standard by combining on-demand hydrogen generation and continuous flow technology within a single instrument. The product family comprises three different reactors, catering to a wide range of user requirements.

The H-Cube Mini Plus stands out for its user-friendly design, offering a modern and streamlined version of its original counterpart. With enhanced ease of use, this instrument ensures efficient small-scale laboratory hydrogenation.

On the other hand, the H-Cube Pro is specifically designed for advanced hydrogenation and complex flow chemical reactions. It provides a wider temperature range, higher hydrogen production rate, and increased flexibility, catering to the diverse needs of users. It's Hastelloy edition ensures improved chemical resistance for advanced applications.

With their cutting-edge features and capabilities, these flow hydrogenation reactors continue the legacy of the H-Cube system, pushing the boundaries of laboratory hydrogenation technology. Over the years, they have been used all around the world for a wide range of applications and have been featured in numerous scientific publications.

H-Cube Mini Plus

Safe and easy hydrogenation

H-Cube Pro

Flow reactor for advanced hydrogenation

H-Cube Pro Hastelloy

Improved chemical resistance for hydrogenation


Reactions with hydrogen gas:

Triple bond full reduction, debenzylation, nitrile reduction, selective nitro reduction, selective triple to double bond reduction, selective double bond reduction, aldose reduction, aromatic heterocycle reduction, aromatic ring reduction, etc.

Other reactions:

Deuteration, Sonogashira coupling, Suzuki coupling, etc.

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