Phoenix Flow Reactor

Versatile and powerful flow reactor

Flow reactor designed for high-temperature/high-pressure reactions

The Phoenix Flow Reactor system is designed for high temperature/high-pressure reactions, enabling the synthesis of novel compounds in a parameter space not achievable with standard laboratory equipment. It offers an extended parameter window (temperature up to 450°C, pressure up to 200 bar) and unparalleled versatility of reactor options for both homogeneous and heterogeneous chemistry. Building on the advantages of the flow chemistry technology, this system makes chemical processes significantly safer.

Phoenix Flow Reactor
Catalyst cartridges for Phoenix flow systems
Loop reactors for homogeneous reactions

Features of the Phoenix Flow Reactor

Extended chemical parameter window: One of the most important advantages of the Phoenix Flow Reactor is the extended chemical parameter window it offers. With temperatures up to 450°C and pressures up to 200 bar, this reactor provides you with unprecedented control over your reactions.

Heterogeneous and homogeneous capabilities: The Phoenix Flow Reactor can be used for both heterogeneous and homogeneous chemical transformations, allowing chemists to tackle a various reaction types. Whether you are working with solid materials and catalysts, or are conducting homogeneous reactions, this system accommodates your needs with ease.

Simple interchange of heated elements: The Phoenix Flow Reactor offers a wide range of heated elements to suit different requirements. You can use PTFE, Hastelloy, or stainless-steel coiled loop reactors of different volumes for homogeneous reactions. User-fillable metal-metal sealed cartridges are available to perform heterogeneous chemistry. CatCarts and MidiCarts ensure convenient and efficient catalyst testing.

User-friendly software interface and movable touch screen: The software of the Phoenix Flow Reactor allows seamless control and monitoring of the reactor parameters. With a movable GUI touch screen, you have the freedom to position the interface wherever it is most convenient for you.

Modularity: The modular design of the Phoenix flow systems enables easy integration with a wide range of  instruments, allowing you to build and customize the system to your needs.

Rapid heating: Heating times are significantly reduced, enabling quicker access to the desired temperature for your reactions. The inclusion of cooling functionality ensures rapid cool-down at the end of the reaction, enhancing productivity and saving time.

Multiple temperature sensors: The Phoenix Flow Reactor gives you the option to monitor temperature with the help of multiple temperature sensors throughout the system, enabling accurate and reliable data acquisition.

Modules for the Phoenix Flow Reactor

H-Genie®: With the H-Genie hydrogen generator, you can use high purity hydrogen gas for your reactions. Hydrogen is generated on-demand from water at pressures up to 100 bar (14.5–1450 psi) and at flow rates up to 1 NL/min.

Gas Module: The Gas Module (max. 100 NmL/min gas flow rate) and the Gas Module Plus (may. 1000 NmL/min gas flow rate) allow the introduction of gases, such as carbon monoxide, oxygen, syngas to the liquid flow. Gases can be used up to 100 bar pressure, widening the reactor’s chemistry capabilities significantly. It is also possible to use more than one Gas Module and mixers to introduce more than one gas at the same time.
Recommended gas regulators: N2 regulator - Linde C200/1A-200B; O2 regulator - Rhöna EN OX 03-10, H2 regulator - Linde fdr-200-100-380-h

Mixer Module: By dispersing gases into fine bubbles, the Mixer Module significantly enhances the effectivity of gas-liquid phase mixing, while also expanding surface area and increasing reaction yields.

Pressure Module: The Pressure Module generates pressure in the reaction chamber. The module contains a system valve, a pressure sensor and a 3-way valve to set the outlet (to waste or to product collection). The maximum pressure is 100/200 bar (depending on other modules used with the Phoenix Flow Reactor).

HPLC pumps: HPLC pumps  are 10 mL/min or 50 mL/min capacity units with built-in pressure sensors (inlet pressure sensors). It is recommended to have extra HPLC pumps if multiple inlets are needed for the choosen application.

System Controller and THS Reaction Software: The System Controller module and the THS ReAction software provide comprehensive control over every individual module within the system. With their help, users can monitor the parameters of each module, enabling seamless integration and optimal performance of the Phoenix Flow System.

Gas Module from ThalesNano
H-Genie hydrogen generator
Mixer Module from ThalesNano

Available heated elements for the Phoenix Flow Reactor

The Phoenix Flow Reactor is a powerful and versatile heating unit capable of reaching temperatures up to 450 °C. A big selection of ready-made reactor setups are available for both homogeneous and heterogeneous applications.

Packed bed reactors: Prefilled CatCarts (30 mm, 70 mm long CatCarts®) and MidiCarts are available for safe and convenient catalyst testing. User-fillable metal-metal sealed cartridges with fittings from 1/8” OD to 1/2” OD with 125 mm and 250 mm lengths can be used for a wide range of heterogeneous reactions. The reactor holder sets are made of four pieces in each case; they are required to fill up the internal volume of the Phoenix Flow Reactor's reaction zone.

Loops: 4, 8,  or 16 or mL PTFE, stainless steel, and Hastelloy loops are available for homogeneous chemistry.

For custom-sized heated elements please contact us at


Basic configuration: SNAr reactions, Boc-removal, Claisen rearrangement, C-alkylation, N-alkylation, supercritical reactions, heterocycle synthesis, etc.

Addition to basic configuration: Hydrogenation, oxidation, carbonylation, etc.


Yes. With the help of as many Gas Modules™ as necessary and applying the Pressure Module™, it is possible to perform catalytic reactions in gas phase at high temperatures and pressures.
No, the Phoenix™ Flow Reactor requires at least a liquid feed and a back-pressure regulator to keep the solvent in the liquid phase.
Yes. If you already own a pump and a back-pressure regulator, you will be able to connect them to the Phoenix™ Flow Reactor.
Both homogeneous and heterogeneous reactions, including SNAr reactions, protecting group removals, rearrangement reactions, alkylation, supercritical reactions, etc. Read our application notes and related publications for more information.
Yes. It is possible to create a completely customized system that fits your own needs. Talk to our application chemists at to find out what would be the perfect configuration for you.

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