Discovery of a series of 8-(1-phenylpyrrolidin-2-yl)-6-carboxamide-2-morpholino-4H-chromen-4-one as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours

Barlaam, B.; Cosulich, S.; Degorce, S.; Ellston, R.; Fitzek, M.; Green, S.; Hancox, U.; Lambert-van der Brempt, C.; Lohmann, J-J.; Maudet, M.; Morgentin, M.; Ple, P.; Ward, L.; Warin, N.; Bioorg. Med. Chem. Lett., 2017, 27(9), 1949-1954

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