ThalesNano signs strategic alliance with NanGenex to offer revolutionary nanosizing continuous flow technology service

October 12nd, 2009 – Budapest, Hungary, London, UK and Princeton, USA – ThalesNano, the world leader in bench top flow chemistry reactor development and related chemistry services, announced today a strategic alliance with NanGenex, a nanoformulation technology company. Through this partnership ThalesNano will immediately begin offering a full range of services from chemical synthesis of compounds to nanosized formulation.

ThalesNano is internationally recognized for offering customers a wide range of specialized chemical services using its state of the art flow reactors. These services include custom synthesis and scale up of difficult or hazardous reactions, automated catalyst screening, library production, and custom instrument development. ThalesNano’s deep chemistry and engineering experience coupled with the wide parameter and scale range of their flow reactors means that ThalesNano can provide novel chemistries, fast optimization, and cost and time effective solutions to many industry problems. In addition to these strengths, ThalesNano is now able to deliver nanoformulated compounds: The NanoActive™ technology from NanGenex eliminates the key issues of low solubility and permeability often faced by otherwise promising API candidates.

The NanoActive™ technology overcomes the failures and shortcomings of the commercially available top-down milling and high pressure homogenization based technologies and the properties of the produced nanoparticles can be modified during the synthesis process by the precise control and optimization of various reaction parameters (e.g. pressure, temperature, flow rate, pH and concentration). This can reduce the time it takes to formulate nano-structured active molecules by as much as 90%.

“This new technology further broadens the scope of ThalesNano’s service portfolio.” said Dr. Laszlo Urge, CEO of ThalesNano Inc. “Our customers will benefit significantly from the opportunity to use these integrated and unique services.”

“We are very happy to work with ThalesNano and make nanoformulation a natural choice to create active molecules with superior characteristics.” Gabor Heltovics, CEO of NanGenex said. “This partnership creates an unparalleled critical mass of flow chemistry and nanoformulation and delivers great value to our customers.”

About ThalesNano Inc.
ThalesNano is the world leader in bench-top flow chemistry reactors. The company has the widest portfolio of continuous process instruments for the pharmaceutical, biotech, fine chemical, petroleum/biofuel and education markets. Its R&D 100 award winning H-Cube® and scale-up system H-Cube Mid™ are used in hundreds of laboratories globally and have become the new industry standard for hydrogenation. Within three years from the original introduction of its flagship H-Cube product, 20 out of the top 20 pharmaceutical companies have introduced and adopted the technology.
Contact: Laszlo Urge, Ph.D., CEO, e-mail: ceodirect@thalesnano.com, Telephone: +36-1-880-8500
More information about ThalesNano can be found at www.thalesnano.com

About NanGenex Inc.
NanGenex is a Proprietary NanoSolution Technology Platform company based and anchored as a member of the oldest and largest technology corporation network in Hungary which was established more than 25 years ago. It provides breakthrough solutions to develop new generations of NanoActive™ products with significant performance benefits over conventional approaches. The company has a unique platform of proprietary technology solutions encompassing the full R&D and commercialization value chain from upstream research and discovery to full scale product manufacturing and commercialization.
Contact: Gábor Heltovics, MBA, CEO, e-mail: info@nangenex.com, Telephone: +36-1-880-8472
More information about NanGenex can be found at www.nangenex.com

Sigma-Aldrich® Partners With Flow Chemistry Leader ThalesNano to Provide CatCart® Catalyst Products for Rapidly Growing Market

Agreement Provides Chemists With Global Access to Next-Generation Flow Chemistry Technology

October 6th, 2009 – Sigma-Aldrich (Nasdaq: SIAL) announced today that it has signed a distribution agreement with ThalesNano, the world leader in bench top flow chemistry instruments, the terms of which will see Sigma-Aldrich distribute ThalesNano’s complete line of approximately 400 CatCart® catalyst products for flow chemistry solutions on a global basis.
ThalesNano flow reactors and CatCart catalyst cartridges provide organic chemists in academic research, large pharmaceutical companies and the chemical and petroleum industries with the means to perform catalytic reactions that are often not possible using traditional batch chemistry processes. Using this technology, chemists can develop new chemicals, or devise faster, better yielding routes and processes to produce existing chemicals.

“Sigma-Aldrich is proud to partner with an innovative company like ThalesNano and to support the next-generation technology of flow chemistry,” said Nigel Mobbs, Sigma-Aldrich Market Segment Manager. “Flow chemistry solutions offer many advantages over traditional methods of performing organic synthesis, delivering better yields and faster reactions, while eliminating many reaction hazards. ThalesNano’s H-Cube®, H-Cube Midi® and X-Cube® flow reactors and CatCart catalyst cartridges give chemists more reactions, with shorter development and scale-up times. Sigma-Aldrich distribution will provide chemists around the world easier access to research and the ability to develop new molecules using these flow reactors and catalysts.”
Dominic Gallello, Executive Co-Chairman at ThalesNano added: “Sigma-Aldrich is a trusted brand recognized around the world. Our goal is to provide our global customers with the availability and rapid delivery of catalysts, critical elements to accelerate the discovery process in a broader range of industries.”

For more information on the complete range of ThalesNano CatCart products offered by Sigma-Aldrich, go to www.sigma-aldrich.com/catcarts.

About Sigma-Aldrich:

Sigma-Aldrich is a leading Life Science and High Technology company. Its biochemical and organic chemical products and kits are used in scientific research, including genomic and proteomic research, biotechnology, pharmaceutical development and as key components in pharmaceutical, diagnostic and other high technology manufacturing. The Company has customers in life science companies, university and government institutions, hospitals, and in industry. Over one million scientists and technologists use its products. Sigma-Aldrich operates in 38 countries and has 7,800 employees providing excellent service worldwide. Sigma-Aldrich is committed to Accelerating Customer Success through Innovation and Leadership in Life Science, High Technology and Service. For more information about Sigma-Aldrich, please visit its award-winning website at http://www.sigma-aldrich.com.

About ThalesNano Inc.:

ThalesNano is the world leader in bench-top flow chemistry reactors. The company has the widest portfolio of continuous process instruments for the pharmaceutical, biotech, fine chemical, petroleum/biofuel and education markets. Its R&D 100 award winning H-Cube® and scale-up system H-Cube Midi® are used in hundreds of laboratories globally and have become the new industry standard for hydrogenation. Within three years from the original introduction of its flagship H-Cube product, 20 out of the top 20 pharmaceutical companies have introduced and adopted the technology.

Contact: Laszlo Urge, Ph.D., CEO, e-mail: ceodirect@thalesnano.com, Telephone: +36-1-880-8500
More information about ThalesNano can be found at www.thalesnano.com

Sigma-Aldrich is a registered trademark of Sigma-Aldrich Biotechnology LP and Sigma-Aldrich Co. CatCart, H-Cube, H-Cube Midi and X-Cube are trademarks of ThalesNano Nanotechnology, Inc.

Donau Lab to Distribute ThalesNano’s Flow Chemistry Reactors in Central Europe and Russia/CIS Countries

October 5th, 2009 – Budapest, Hungary, London, UK, Princeton, US and Zurich, Switzerland – ThalesNano, the world leader in bench top flow chemistry reactors and Donau Lab AG, one of the largest providers of scientific instruments in Eastern Europe and CIS Countries announced today that Donau Lab will distribute ThalesNano’s award winning product line.

“We are very excited about forming a partnership with Donau Lab said Dominic Gallello, Executive Co-Chairman of ThalesNano. “Having an established brand like Donau to sell and support ThalesNano’s product is very important for our customers and potential customers. Donau’s scientific competence will help to insure that users can rapidly achieve great results”.

“We have been representing leading scientific product companies in the region for more than 30 years”, said Peter Gerwig, President of Donau Labs. “We are delighted to add the ThalesNano product line to our solutions offering. Our customers are always interested in being introduced to new technology that will leap them forward in organic synthesis and catalyst development. ThalesNano’s products match this need very well”.

About ThalesNano Inc.
ThalesNano is the world leader in bench-top flow chemistry reactors. The company has the widest portfolio of continuous process instruments for the pharmaceutical, biotech, fine chemical, petroleum/biofuel and education markets. Its R&D 100 award winning H-Cube® and scale-up system H-Cube Midi® are used in hundreds of laboratories globally and have become the new industry standard for hydrogenation. Within three years from the original introduction of its flagship H-Cube product, 20 out of the top 20 pharmaceutical companies have introduced and adopted the technology.
Contact: Laszlo Urge, Ph.D., CEO, e-mail: ceodirect@thalesnano.com, Telephone: +36-1-880-8500

About Donau Lab Group
Donau Lab Group has more than 30 years of tradition and experience in distributing and servicing high quality laboratory equipment. The company has 17 offices and more than 150 employees, covering all 28 countries of Central Europe and Russia/CIS. The portfolio of Donau Lab includes products of global market leaders, producing dedicated instruments for application fields such as synthetic chemistry, biotechnology, microbiology, analytical chemistry and pharmaceutical technology. Donau’s close partnership with its suppliers and the high competence of its employees help to insure customer success.
Contact: Jozsef Papp, Central Product Manager, email: papj@donaulab.com, Telephone: +36-1-319-1718