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Multigram-scale flow synthesis of the chiral key intermediate of (−)-paroxetine enabled by solvent-free heterogeneous organocatalysis

Otvos, S. B.; Pericas, M. A.; Kappe, C. O.; Chem. Sci., 2019, 10, 11141-11146

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The continuous synthesis and application of graphene supported palladium nanoparticles: a highly effective catalyst for Suzuki-Miyaura cross-coupling reactions

Brinkley, K. W.; Burkholder, M.; Siamaki, A. R.; Belecki, K.; Gupton, B. F.; Green Process. Synth., 2015, 4(3), 241-246

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Facile arene hydrogenation under flow conditions catalyzed by rhodium or ruthenium on carbon

Hattori, T.; Ida, T.; Tsubone, A.; Sawama, Y.; Monguchi, Y.; Sajiki, H.; Eur. J. Org. Chem., 2015, 2015(11), 2492-2497

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Catalytic asymmetric crotylation of aldehydes: Application in total synthesis of (−)‐elisabethadione

O’Hora, P. S.; Incerti‐Pradillos, C. A.; Kabeshov, M. A.; Shipilovskikh, S. A.; Rubtsov, A. E.; Elsegood, M. R. J; Malkov, A. V.; Chem. Eur. J., 2015, 21(12), 4551-4555

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Nafion‐H‐catalyzed high‐temperature/high‐pressure synthesis of a triarylmethane in continuous‐flow mode

Hayden, S.; Glasnov, T.; Kappe, C. O.; Chem. Eng. Technol., 2015, 38(10), 1743-1748

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Synthesis and activity of putative small-molecule inhibitors of the F-Box protein SKP2

Shouksmith, A. E.; Evans, L. E.; Tweddle, D. A.; Miller, D. C.; Willmore, E.; Newell, D. R.; Golding, B. T.; Griffin, R. J.; Aust. J. Chem., 2015, 68(4), 660-679

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Synthesis and structure-activity relationship studies of N-benzyl-2-phenylpyrimidin-4-amine derivatives as potent USP1/UAF1 deubiquitinase inhibitors with anticancer activity against nonsmall cell lung cancer

Dexheimer, T. S.; Rosenthal, A. S.; Luci, D. K.; Liang, Q.; Villamil, M. A.; Chen, J.; Sun, H.; Kerns, E. H.; Simeonov, A.; Jadhav, a.; Zhuang, Z.; Maloney, D. J.; J. Med. Chem., 2014, 57(19), 8099-8110

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Self-optimizing reactor systems: Algorithms, on‐line analytics, setups, and strategies for accelerating continuous flow process optimization

Fabry, D. C.; Sugiono, E.; Ruepig, M.; Isr. J. Chem., 2014, 54(4), 341-350

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Carbonylation in microflow: close encounters of CO and reactive species

Fukuyama, T.; Totoki, T.; Ryu, I.; Green Chemistry, 2014, 16, 2042-2050

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Immobilized transition metals as catalysts for cross-couplings in continuous flow — A critical assessment of the reaction mechanism and metal leaching

Cantillo, D.; Kappe, C. O.; ChemCatChem, 2014, 6(12), 3286-3305

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