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  1. Home ›
  2. Publication
  3. : Page 50

Acylguanidine beta secretase 1 inhibitors: a combined experimental and free energy perturbation study

Keranen, H.; Perez-Benito, L.; Ciordia, M.; Delgado, F.; Steinbrecher, T. B.; Oehlrich, D.; van Vlijmen, H. W. T.; Trabanco, A. A.; Tresadern, G.; J. Chem. Theory Comput., 2017, 13, 1439-1453

Link to article

Environmentally friendly synthesis of indoline derivatives using flow-chemistry techniques

Orkenyi, R.; Beke, G.; Riethmuller, E.; Szakacs, Z.; Koti, J.; Faigl, F.; Eles, J.; Greiner, I.; Eur. J. Org. Chem., 2017, 6525-6532

Link to article

Discovery of a series of 8-(1-phenylpyrrolidin-2-yl)-6-carboxamide-2-morpholino-4H-chromen-4-one as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours

Barlaam, B.; Cosulich, S.; Degorce, S.; Ellston, R.; Fitzek, M.; Green, S.; Hancox, U.; Lambert-van der Brempt, C.; Lohmann, J-J.; Maudet, M.; Morgentin, M.; Ple, P.; Ward, L.; Warin, N.; Bioorg. Med. Chem. Lett., 2017, 27(9), 1949-1954

Link to article

Chemoselective flow hydrogenation approaches to diversify the cytotoxic tetrahydroepoxyisoindole carboxamide scaffold

Spare, L. K.; Harman, D. G.; Aldrich-Wright, J. R.; Nguyen, T. V.; Gordon, C. P.; Adv. Synth. Catal., 2018, 360(6), 1209-1217

Link to article

Highly selective hydrogenation of R‑(+)-limonene to (+)-p- 1‑menthene in batch and continuous flow reactors

Rubulotta, G.; Luska, K. L.; Urbina-Blanco, C. A.; Eifert, T.; Palkovits, R.; Quadrelli, E. A.; Thieuleux, C.; Leitner, W.; ACS Sustainable Chem. Eng., 2017, 5, 3762-3767

Link to article

General methods for the synthesis and late-stage diversification of 2,4-substituted 7-azaindoles

Varnes, J. G.; McGuire, T.; Meadows, R. E.; Barlaam, B.; Clark, J.; Cook, C. R.; Davison, G.; Dishington, A.; De Savi, C.; Donald, C.; Grebe, T.; Hande, S.; Hawkins, J.; Hird, A. W.; Holmes, J.; Lister, A.; Lucas, S.; Moore, J.; Moore, E.; Patel, A.; Pike, K. G.; Roberts, B.; Stark, A.; Stead, D.; Thakur, K.; Turner, P.; Vasbinder, M.; Yang, B.; Tetrahedron Letters, 2016, 57, 4718-4722

Link to article

Chemical synthesis of the 4-amino-4,6-dideoxy-d-glucose containing pentasaccharide repeating unit of the O-specific polysaccharide from Aeromonas hydrophila strain K691 in the form of its 2-aminoethyl glycoside

Adak, A.; Mukhopadhyay, B.; Carbohydrate Research, 2019, 476, 1-7

Link to article

Emerging trends in flow chemistry and applications to the pharmaceutical industry

Bogdan, A. R.; Dombrowski, A. W.; J. Med. Chem., 2019, 62(14), 6422-6468

Link to article

Harnessing the versatility of continuous-flow processes: selective and efficient reactions

Mandity, I. M.; Otvos, S. B.; Szolosi, G.; Fulop, F.; Chem. Rec., 2016, 16, 1018-1033

Link to article

Design and development of Pd-catalyzed aerobic N-demethylation strategies for the synthesis of noroxymorphone in continuous flow mode

Gutmann, B.; Cantillo, D.; Weigl, U.; Cox, P.; Kappe, C. O.; Eur. J. Org. Chem., 2017, 914-927

Link to article

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