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Reductive amination in the synthesis of pharmaceuticals

Afanasyev, O. I.; Kuchuk, E.; Usanov, D. L.; Chusov, D.; Chem. Rev., 2019, 119(23), 11857-11911

Link to article

In situ sulfidation of Pd/C: A Straightforward method for chemoselective conjugate reduction by continuous hydrogenation

Moore, J. C.; Howie, R. A.; Bourne, S. L.; Jenkins, G. N.; Licence, P.; Poliakoff, M.; George, M. W.; ACS Sustainable Chem. Eng., 2019, 7(19), 16814-16819

Link to article

Multi-step solvent-free 3 m2 footprint pilot miniplant for the synthesis of annual half ton rufinamide precursor

Gelonch, M. E.; de Leon Izeppi, G. A.; Kirschneck, D.; Hessel, V.; ACS Sustainable Chem. Eng., 2019, 7(20), 17237-17251

Link to article

Cobalt-doped magnesium fluoride as a support for platinum catalysts: The correlation of surface acidity with hydrogenation activity

Pietrowski, M.; Zieliński, M.; Alwina, E.; Gulaczyk, I.; Przekop, R. E.; Wojciechowska, M.; J. Cat., 2019, 378, 298-311

Link to article

A comparative assessment study of known small-molecule Keap1−Nrf2 protein–protein interaction inhibitors: Chemical synthesis, binding properties, and cellular activity

Tran, K. T.; Pallesen, J. S.; Solbak, S. M. O.; Narayanan, D.; Baig, A.; Zang, J.; Aguayo-Orozco, A.; Carmona, R. M. C.; Garcia, A. D.; Bach, A.; J. Med. Chem., 2019, 62(17), 8028-8052

Link to article

Convergent synthesis of the hexasaccharide repeating unit of the O-antigenic OPS of Escherichia coli O133

Mitra, A.; Mukhopadhyay, B.; Eur. J. Org. Chem., 2019, 2019(30), 4869-4878

Link to article

A Warburg effect targeting vector designed to increase the uptake of compounds by cancer cells demonstrates glucose and hypoxia dependent uptake

Glenister, A.; Simone, M. I.; Hambley, T. W.; PLos One, 2019, online article

Link to article

Continuous flow selective hydrogenation of 5-hydroxymethylfurfural to 2,5-dimethylfuran using highly active and stable Cu-Pd/reduced graphene oxide

Mhadmhan, S.; Franco, A.; Pineda, A.; Reubroycharoen, P.; Luque, R.; ACS Sustainable Chem. Eng., 2019, 7(16), 14210-14216

Link to article

Asymmetric organocatalytic Michael addition–cyclisation cascade of cyclopentane-1,2-dione with alkylidene malononitriles

Silm, E.; Kaabel, S.; Jarving, I.; Kanger, T.; Synthesis, 2019, 51, 4198-4204

Link to article

Adaptive and automated system-optimization for heterogeneous flow-hydrogenation reactions

Fabry, D. C.; Heddrich, S.; Sugiono, E.; Liauw, M. A.; Rueping, M.; React. Chem. Eng., 2019, 4, 1486-1491

Link to article

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