McNutt, J.; He, Q.; J. Ind. Eng. Chem., 2016, 36, 1-12
Insights into the selective hydrogenation of levulinic acid to γ-valerolactone using supported mono- and bimetallic catalysts
Al-Naji, M.; Yepez, A.; Balu, A. M.; Romero, A. A.; Chen, Z.; Wilde, N.; Li, H.; Shih, K.; Glaser, R.; Luque, R.; Journal of Molecular Catalysis A: Chemical, 2016, 417, 145-152
Total synthesis and biological evaluation of tubulysin analogues
Colombo, R.; Wang, Z.; Han, J.; Balachandran, R.; Daghestani, H. N.; Camarco, D. P.; Vogt, A.; Day, B. W.; Mendel, D.; Wipf, P.; J. Org. Chem., 2016, 81(21), 10302-10320
Optically pure, structural, and fluorescent analogues of a dimeric Y4 receptor agonist derived by an olefin metathesis approach
Liu, M.; Mountford, S. J.; Richardson, R. R.; Groenen, M.; Holliday, N. D.; Thompson, P. E.; J. Med. Chem., 2016, 59(13), 6059-6069
Structure-activity relationship studies of mitogen activated protein kinase interacting kinase (MNK) 1 and 2 and BCR-ABL1 inhibitors targeting chronic myeloid leukemic cells
Cherian, J.; Nacro, K.; Poh, Z. Y.; Guo, S.; Jeyaray, D. A.; Wong, Y. X.; Ho, M.; Yang, H. Y.; Joy, J. K.; Kwek, Z. P.; Liu, B.; Wee, J. L. K.; Ong, E. H.; Choong, M. L.; Poulsen, A.; Lee, M. A.; Pendharkar, V.; Ding, L. J.; Manoharan, V.; Chew, Y. S.; Sangthongpitag, K.; Lim, S.; Ong, S. T.; Hill, J.; Keller, T. H.; J. Med. Chem., 2016, 59(7), 3063-3078
Discovery of narrow spectrum kinase inhibitors: New therapeutic agents for the treatment of COPD and steroid-resistant asthma
Onions, S. T.; Ito, K; Charron, C. E.; Brown, R. J.; Colucci, M.; Frickel, F.; Hardy, G.; Joly, K.; King-Underwood, J.; Kizawa, Y.; Knowles, I.; Murray, P. J.; Novak, A.; Rani, A.; Rapeport, G.; Smith, A.; Strong, P.; Taddei, D. M.; Williams, J. G.; J. Med. Chem., 2016, 59(5), 1727-1746
Discovery of a novel inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) as orally active antitumor agent
Vianello, P.; Botrugno, O. A.; Cappa, A.; Zuffo, R. D.; Dessanti, P.; Mai, A.; Marrocco, B.; Mattevi, A.; Meroni, G.; Minucci, S.; Stazi, G.; Thaler, F.; Trifiro, P.; Valente, S.; Villa, M.; Mercurio, C.; J. Med. Chem., 2016, 59(4), 1501-1517
Nanopalladium-catalyzed conjugate reduction of Michael acceptors – application in flow
Nagendiran, A.; Sorensen, H.; Johansson, M. J.; Tai, C-W.; Backvall, J-E.; Green Chem., 2016, 18(9), 2632-2637
Nitroimidazole carboxamides as antiparasitic agents targeting Giardia lamblia, Entamoeba histolytica and Trichomonas vaginalis
Jarrad, A. M.; Debnath, A.; Miyamoto, Y.; Hansford, K. A.; Pelington, R.; Butler, M. S.; Bains, T.; Karoli, T.; Blaskovich, M. A. T.; Eckmann, L.; Cooper, M. A.; Eur. J. Med. Chem., 2016, 120, 353-362
Discovery and antiplatelet activity of a selective PI3Kβ inhibitor (MIPS-9922)
Zheng, Z.; Pinson, J. A.; Mountford, S. J.; Orive, S.; Schoenwaelder, S. M.; Shackleford, D.; Powell, A.; Nelson, E. M.; Hamilton, J. R.; Jackson, S. P.; Jennings, I. G.; Thompson, P. E.; Eur. J. Med. Chem., 2016, 122, 339-351