May 7th, 2009 – Budapest, Hungary, London, UK, Princeton, US – A collaboration between groups led by Dr John Spencer at Greenwich University and Professor Simon Mackay and Professor Alan Harvey at Strathclyde University has led to the discovery of a novel class of benzodiazepines with submicromolar activity against trypanosoma brucei spp. a parasitic species that causes African trypanosomiasis or sleeping sickness in humans.

Dr. John Spencer, Reader in Medicinal Chemistry, said “Rajendra Rathnam, one of my PhD students at Greenwich, has successfully synthesized a number of benzodiazepine containing amines by a variety of reduction methods from their nitro precursors including microwave reductions with Mo(CO)₆/DBU or SnCl₂.2H₂O, but the H-Cube® flow method provided compounds in approximately 5 minutes in high yields and without the need for work-up or column chromatography. Such an approach is very promising for the generation of libraries of bioactive molecules and can expedite drug discovery significantly”

The work was recently presented at the prestigious MedChem Europe 2009 Conference in Berlin (organized by Select Biosciences).

“We are proud that our technology can play an important role in advancing science said Richard Jones, Director of Product Management at ThalesNano. From its introduction, H-Cube® has opened up vast new areas of chemistry due to its advantages of speed, selectivity and yield.”

About ThalesNano Inc.

ThalesNano www.thalesnano.com is a world-leading provider of continuous process chemistry instruments in the rapidly developing market of laboratory and process scale flow chemistry reactors. The company has the widest portfolio of bench-top continuous process chemistry instruments. Its R&D 100 award winning H-Cube® continuous-flow hydrogenation reactor and the pilot plant scale version H-Cube Midi® are used in hundreds of laboratories in four continents and have become the new industry standard for hydrogenation.

Contact: Laszlo Urge, Ph.D., CEO, e-mail: ceodirect@thalesnano.com, Telephone: +36-1-880-8500

April 28th, 2009- Budapest, Hungary, London, UK, Princeton, US and Singapore – ThalesNano, the world leader in bench top flow chemistry reactors and ITS Group, a leading provider of scientific instruments for organic synthesis and analysis, announced today that ITS Group will distribute ThalesNano’s award winning product line in the ASEAN Region.

“We are delighted to have the largest supplier of scientific instruments in the region committed to bring our flow chemistry solutions to users”, said Dominic Gallello, Executive Co-Chairman of ThalesNano, Inc. The Singapore, Malaysia, Thailand, Indonesia and Vietnam markets offer tremendous opportunities.”

“We see many possibilities in the region with the rapid development of the pharmaceutical, biotech, chemical and petroleum industries”, said Lawrence Tan, Founder and President of ITS Group. “Companies and research institutes are looking for new and better ways to perform organic synthesis. Our organization of nearly 200 chemists, sales and support personnel are excited to take our customers to a new level in discovery and scale up.”

About ThalesNano Inc.

ThalesNano www.thalesnano.com is a world-leading provider of continuous process chemistry instruments in the rapidly developing market of laboratory and process scale flow reactors. The company has the widest portfolio of bench-top continuous process instruments. Its R&D 100 award winning H-Cube® continuous-flow hydrogenation reactor and the pilot plant scale version H-Cube Midi® are used in hundreds of laboratories in four continents and have become the new industry standard for hydrogenation.

Contact: Laszlo Urge, Ph.D., CEO, e-mail: ceodirect@thalesnano.com, Telephone: +36-1-880-8500

About ITS Group

ITS Group is a leading scientific equipment distributor and integrated scientific solution provider in Asia, with more then 30 years of experience as the Asia representative for top manufacturers from USA, Europe and Asia. ITS has an established operation network and warehouses strategically located in Singapore, Malaysia, Indonesia, Thailand, Vietnam, China and Philippines, together with our team of highly trained technical sales representatives and service engineers, we have been the reliable partner, offering unparallel services and innovative solutions to our customers in the universities, research institutions and government agencies, pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, as well as environmental and industrial quality testing settings. Please visit us at www.its-asia.com.

CM Corporation Ltd. to Distribute World Leader ThalesNano’s Products in South Korea

April 16th, 2009- Budapest, Hungary, London, UK, Princeton, US and Seoul, South Korea- ThalesNano, the world leader in bench top flow chemistry reactors and CM Corporation Ltd, a leading provider of scientific instruments for organic synthesis and analysis, announced today that CM Corporation Ltd. will distribute ThalesNano’s award winning product line in South Korea.

“We are delighted to be working with CM Corporation Ltd. who will be at the forefront in offering users disruptive innovation with our flow reactors”, said Dominic Gallello, Executive Co-Chairman of ThalesNano, Inc. Korean chemists who have typically been avoiding dangerous hydrogenation, will now find a safe and an extremely fast solution for creating and scaling up new compounds that they could previously not realize.”

“There are many opportunities in pharmaceutical, education & research, chemical and petrochemical areas to introduce ThalesNano’s innovative flow chemistry reactors”, said Mr H.R. Moh, President of CM Corporation Ltd. Our users area already excited with the potential benefits of speed, safety, rapid scale up, and the ability to expand the chemical space.”

About ThalesNano Inc.

ThalesNano www.thalesnano.com is a world-leading provider of continuous process chemistry instruments in the rapidly developing market of laboratory and process scale flow reactors. The company has the widest portfolio of bench-top continuous process instruments. Its R&D 100 award winning H-Cube® continuous-flow hydrogenation reactor and the pilot plant scale version H-Cube Midi® are used in hundreds of laboratories in four continents and have become the new industry standard for hydrogenation.

Contact: Laszlo Urge, Ph.D., CEO, e-mail: ceodirect@thalesnano.com, Telephone: +36-1-880-8500

About CM Corporation Ltd.

CM Corporation Ltd. (www.cm-corp.co.kr) was established in 2000 to bring world leading scientific instruments to the South Korean market. CM Corporation Ltd. prides itself on the technical competence of its staff who provide customers with high levels of support.

Contact: H.R.Moh , e-mail:hrmoh@cm-corp.co.kr, Tel.+82-(0)2-451-9001

Zinsser Analytic and ThalesNano Collaborate on Distributing Products

March 27th, 2009 – Frankfurt Germany and Budapest, Hungary, London, UK, Princeton NJ – Zinsser Analytic and ThalesNano today announced the signing of a collaboration agreement for product distribution in the territory of Germany, Switzerland and Austria.

“We are very proud and excited about partnering with Zinsser Analytic. Zinsser is a leader in automation and a brand recognized in the industry around the world”, – said Dr. Ferenc Darvas, president and chairman of ThalesNano Inc. – “Our business in the region has been growing very rapidly and Zinsser will be providing our customers with high quality support that Zinsser is well known for.

“We are looking to provide innovative solutions for our pharmaceutical, agrochemical, chemical and academic customers”, Werner Zinsser, CEO and president of Zinsser Analytic, said. “ThalesNano’s award winning continuous chemistry products for organic synthesis offer users dramatic speed improvements, safety, rapid scale up, and the ability to expand the chemical space.”

Zinsser Analytic will be exhibiting the ThalesNano product line at ACHEMA 2009 , Frankfurt / Germany

About ThalesNano Inc.:

ThalesNano www.thalesnano.com is a world-leading provider of continuous process chemistry instruments in the rapidly developing market of laboratory and process scale flow reactors. The company has the widest portfolio of bench-top continuous process instruments. Its R&D 100 award winning H-Cube® continuous-flow hydrogenation reactor and the pilot plant scale version H-Cube Midi® are used in hundreds of laboratories in four continents and have become the new industry standard for hydrogenation.

Contact: Laszlo Urge, Ph.D., CEO, e-mail: ceodirect@thalesnano.com, Telephone: +36-1-880-8500

About Zinsser Analytic GmbH:

Zinsser Analytic www.zinsser-analytic.com is an international company well known for systems in drug discovery and material science. Zinsser has offices in Germany, the United Kingdom, France and the USA.

Contact: W.Zinsser, Ceo & President, e-mail: info@zinsser-analytic.com, Telephone: +49-69-7891060

February 9th, 2009 – Budapest, Hungary, London, UK, Princeton NJ

ThalesNano today announced a big step forward in the evolution of flow chemistry with the independent publication of results that prove that flow chemistry can match microwave chemistry in terms of speed, but with the ability to scale up in one continuous process.

The scientific paper, written by Prof. Oliver Kappe’s group at the University of Graz and published in Chemistry: A European Journal, details how the X-Cube Flash™ is able to match reaction time, conversion, and selectivity results with microwave in an important synthetic process: a Mizoroki-Heck cross coupling. The reaction may be then scaled up by either running the reaction in continuous mode until the desired amount of compound has been made or by using larger loop sizes and flow rates to increase throughput.

“Our aim was to solve this major industry process issue and these results prove that we have begun to achieve our goal”, said Richard Jones, Director of Product Management at ThalesNano. “Our users now have the possibility to scale up difficult reactions very quickly and effectively and synthesize hundreds of grams of material a day by implementing this new capability.”

The full paper can be downloaded here.

The X-Cube Flash™ is a high temperature, high pressure continuous flow reactor, developed by ThalesNano Inc. to perform homogeneous organic synthesis. The X-Cube Flash™ is capable of 350°C and 200 bar. The system uses ThalesNano’s patented precise and quick temperature adjustment technology. Chemists can access new chemical space by working safely and conveniently at temperatures and pressures that were not easily accessible before in standard laboratories.

For more information please go to: www.thalesnano.com

About ThalesNano Inc.:
ThalesNano is a world-leading provider of continuous process chemistry instruments in the rapidly developing market of laboratory and process scale flow reactors. The company has the widest portfolio of bench-top continuous process instruments. Its R&D 100 award winning H-Cube® continuous-flow hydrogenation reactor and the pilot plant scale version H-Cube Mid™ are used in hundreds of laboratories in four continents and have become the new industry standard for hydrogenation.
Contact: Richard Jones, e-mail: flowchemistry@thalesnano.com, Telephone: +36-1-880-8500

January 26th, 2009 – Budapest, Hungary, London, UK, Princeton NJ – Attendees from throughout the world gathered this week in Budapest, Hungary for ThalesNano’s inaugural Distributor Conference.

“The attendance underscores the dual momentum of flow chemistry and ThalesNano as the leader in delivering flow chemistry technologies that have already helped our clients to realise great results in terms of speed, selectivity and safety” said Carl Jones, Head of Sales for ThalesNano.

The 2009 ThalesNano Distributor Conference climaxed with an awards ceremony in which partners were honored for their outstanding achievements in promoting and expanding the use of ThalesNano technology. Winners included Inkarp Instruments Pvt. Ltd of India as Distributor of the Year and Serlabo Technologies of France as European Distributor of the Year,

For more information please go to: www.thalesnano.com

About ThalesNano Inc.:
ThalesNano is a world-leading provider of continuous process chemistry instruments in the rapidly developing market of laboratory and process scale flow reactors. The company has the widest portfolio of bench-top continuous process instruments. Its R&D 100 award winning H-Cube® continuous-flow hydrogenation reactor and the pilot plant scale version H-Cube Midi® are used in hundreds of laboratories in four continents and have become the new industry standard for hydrogenation.
Contact: Laszlo Urge, Ph.D., CEO, e-mail: ceodirect@thalesnano.com, Telephone: +36-1-880-8500

WuXi AppTec Selects H-Cube from ThalesNano for Laboratory-based Hydrogenation

January 6th , 2009 – Shanghai, China, Budapest, Hungary, London, UK, Princeton NJ – WuXi AppTec, the operating company of WuXi PharmaTech (NYSE: WX), a leading pharmaceutical, biotechnology and medical device research and development outsourcing company with operations in China and the United States, today announced its selection of H-Cube from ThalesNano Inc. for laboratory-based hydrogenation. WuXi joins all of the top 20 pharmaceutical companies worldwide that have introduced and adopted the H-Cube technology.

“WuXi Apptec is one of the largest CRO companies in the world, providing best in class services to pharmaceutical, biotechnology and medical device research and development industries. We are delighted to supply WuXi with our technology and services”, commentted Dr. Laszlo Urge, CEO of ThalesNano Inc.

“We are very pleased to deploy H-Cube. Hydrogenation in flow for drug discovery is a significantly more productive and safer approach than traditional batch-based techniques. We are looking forward to working with ThalesNano as we move to larger scale in the future,” commented Shuhui Chen, Chief Scientific Officer of WuXi AppTec.

The H-Cube Continuous-flow Hydrogenation Reactor is a bench-top standalone hydrogenation device, uniquely combining continuous-flow microchemistry with endogenous on-demand hydrogen generation and a disposable catalyst cartridge system. Compared to conventional methods, it allows safer, faster and more cost-efficient hydrogenation with superior yield. The H-Cube and the other novel Cube series flow reactor systems developed by ThalesNano Inc. are showing tremendous benefits in the drug discovery process including shortened development time, increased cost efficiency and reduced environmental impact.

For more information please go to: www.thalesnano.com

About ThalesNano Inc.:
ThalesNano is a world-leading provider of continuous process chemistry instruments in the rapidly developing market of laboratory and process scale flow reactors. The company has the widest portfolio of bench-top continuous process instruments. Its R&D 100 award winning H-Cube® continuous-flow hydrogenation reactor and the pilot plant scale version H-Cube Mid™ are used in hundreds of laboratories in four continents and have become the new industry standard for hydrogenation.
Contact: Laszlo Urge, Ph.D., CEO, e-mail: ceodirect@thalesnano.com, Telephone: +36-1-880-8500