M.A.D. Technology (Pty) Ltd to Distribute ThalesNano’s Flow Chemistry Reactors in South Africa

December 7th, 2009 – Budapest, Hungary, London, UK, Princeton, US and Johannesburg, South Africa – ThalesNano, the world leader in bench top flow chemistry reactors and M.A.D. Technology (Pty) Ltd, which provides visionary technology for today’s analytical laboratory and process control applications, announced today that M.A.D. Technology will distribute ThalesNano’s award winning product line.

“We are very excited about forming a partnership with M.A.D. Technology” said Carl Jones, Head of Sales for ThalesNano. “Having an established company like M.A.D. to sell and support ThalesNano’s product is very important for our customers and potential customers. M.A.D.’s scientific competence will help to insure that users can rapidly achieve great results”.

“We are proud to be appointed as a partner to ThalesNano and add their world leading products to our portfolio” said Bruce Hunter, Director of M.A.D. Technology. “Our aim is to establish ThalesNano in our territory as the leading product as we have done with our other partnerships. We look forward to a fruitful and successful future between ThalesNano and M.A.D Technology.”

About ThalesNano Inc.

ThalesNano is the world leader in bench-top flow chemistry reactors. The company has the widest portfolio of continuous process instruments for the pharmaceutical, biotech, fine chemical, petroleum, biofuel and education markets. Its R&D 100 award winning H-Cube® and scale-up system H-Cube Mid™ are used in hundreds of laboratories globally and have become the new industry standard for hydrogenation. Within three years from the original introduction of its flagship H-Cube product, 20 out of the top 20 pharmaceutical companies have introduced and adopted the technology.

Contact: Laszlo Urge, Ph.D., CEO, e-mail: ceodirect@thalesnano.com, Telephone: +36-1-880-8500

About M.A.D. Technology (Pty) Ltd.

M.A.D Technology (Pty) Ltd. provides visionary technology for today’s analytical laboratory and process control applications. In partnership with CEM, they are recognised as the worldwide leader in advanced microwave laboratory instrumentation. As a specialist company providing only niche products we are able to provide the best possible service and support. M.A.D was formed in 2000 and has grown dramatically and is recognized as the leading supplier of microwave and laser systems in Sub-Saharan Africa and the Indian Ocean Islands.

Contact: Bruce Hunter, Director, email: bruce@madtech.co.za, Tel: +27 11 797 3660

PyNN Corporation to distribute ThalesNano’s Flow Chemistry Reactors in China

November 30th, 2009 – Budapest, Hungary, London, UK, Princeton, US, Beijing, China – ThalesNano, the world leader in bench top flow chemistry reactors announced today that PyNN Corporation, one of the largest providers of scientific instruments in China, will begin distributing it’s award winning product line.

“We are very excited about forming a partnership with PyNN Co.”, said Carl Jones, Head of Sales for ThalesNano. “Having an established company like PyNN Co. to sell and support ThalesNano’s range of continuous flow reactors in to the China marketplace is very important for our customers and potential customers. PyNN Co.’s scientific competence will help ensure that users can rapidly achieve and maintain great results.”

According to Laurence Liu, President of PyNN Co., “We’ve met people working with batch reactors in many labs in China. ThalesNano’s flow reactors and professional application support, together with PyNN Co’s marketing efforts, will bring new methods and options to these people. We anticipate ThalesNano continuous flow reactors to be a welcome for chemistry laboratory scientists.”

About ThalesNano Inc.:

ThalesNano is the world leader in bench-top flow chemistry reactors. The company has the widest portfolio of continuous process instruments for the pharmaceutical, biotech, fine chemical, petroleum, biofuel and education markets. It’s R&D 100 award-winning H-Cube® and scale-up system H-Cube Mid™ are used in hundreds of laboratories globally and have become the new industry standard for hydrogenation. Within three years from the original introduction of its flagship H-Cube product, 20 out of the top 20 pharmaceutical companies have introduced and adopted the technology.

Contact: Laszlo Urge, Ph.D., CEO, Email: ceodirect@thalesnano.com, Telephone: +36-1-880-8500.

About PyNN Corporation:

PyNN CORP, the very important partner of ThalesNano in global market. Since the foundation of PyNN, the corporation was committed to the top-class analytical laboratory instrumentation and technology. The Company’s products are widely used in such industries as pharmaceutical, biotech, chemical, environmental, and food processing, as well as for academic research.
PyNN has set branches in Beijing, Shanghai, Guangzhou, and Chengdu of China. The experienced management team, strong technology support and good relations with customers have set the deep basis for the development of the corporation.

Contact: Mrs. Zhang, Email: sales@pynnco.com, Telephone: +86-010-65528800

ThalesNano signs strategic alliance with NanGenex to offer revolutionary nanosizing continuous flow technology service

October 12nd, 2009 – Budapest, Hungary, London, UK and Princeton, USA – ThalesNano, the world leader in bench top flow chemistry reactor development and related chemistry services, announced today a strategic alliance with NanGenex, a nanoformulation technology company. Through this partnership ThalesNano will immediately begin offering a full range of services from chemical synthesis of compounds to nanosized formulation.

ThalesNano is internationally recognized for offering customers a wide range of specialized chemical services using its state of the art flow reactors. These services include custom synthesis and scale up of difficult or hazardous reactions, automated catalyst screening, library production, and custom instrument development. ThalesNano’s deep chemistry and engineering experience coupled with the wide parameter and scale range of their flow reactors means that ThalesNano can provide novel chemistries, fast optimization, and cost and time effective solutions to many industry problems. In addition to these strengths, ThalesNano is now able to deliver nanoformulated compounds: The NanoActive™ technology from NanGenex eliminates the key issues of low solubility and permeability often faced by otherwise promising API candidates.

The NanoActive™ technology overcomes the failures and shortcomings of the commercially available top-down milling and high pressure homogenization based technologies and the properties of the produced nanoparticles can be modified during the synthesis process by the precise control and optimization of various reaction parameters (e.g. pressure, temperature, flow rate, pH and concentration). This can reduce the time it takes to formulate nano-structured active molecules by as much as 90%.

“This new technology further broadens the scope of ThalesNano’s service portfolio.” said Dr. Laszlo Urge, CEO of ThalesNano Inc. “Our customers will benefit significantly from the opportunity to use these integrated and unique services.”

“We are very happy to work with ThalesNano and make nanoformulation a natural choice to create active molecules with superior characteristics.” Gabor Heltovics, CEO of NanGenex said. “This partnership creates an unparalleled critical mass of flow chemistry and nanoformulation and delivers great value to our customers.”

About ThalesNano Inc.
ThalesNano is the world leader in bench-top flow chemistry reactors. The company has the widest portfolio of continuous process instruments for the pharmaceutical, biotech, fine chemical, petroleum/biofuel and education markets. Its R&D 100 award winning H-Cube® and scale-up system H-Cube Mid™ are used in hundreds of laboratories globally and have become the new industry standard for hydrogenation. Within three years from the original introduction of its flagship H-Cube product, 20 out of the top 20 pharmaceutical companies have introduced and adopted the technology.
Contact: Laszlo Urge, Ph.D., CEO, e-mail: ceodirect@thalesnano.com, Telephone: +36-1-880-8500
More information about ThalesNano can be found at www.thalesnano.com

About NanGenex Inc.
NanGenex is a Proprietary NanoSolution Technology Platform company based and anchored as a member of the oldest and largest technology corporation network in Hungary which was established more than 25 years ago. It provides breakthrough solutions to develop new generations of NanoActive™ products with significant performance benefits over conventional approaches. The company has a unique platform of proprietary technology solutions encompassing the full R&D and commercialization value chain from upstream research and discovery to full scale product manufacturing and commercialization.
Contact: Gábor Heltovics, MBA, CEO, e-mail: info@nangenex.com, Telephone: +36-1-880-8472
More information about NanGenex can be found at www.nangenex.com

Sigma-Aldrich® Partners With Flow Chemistry Leader ThalesNano to Provide CatCart® Catalyst Products for Rapidly Growing Market

Agreement Provides Chemists With Global Access to Next-Generation Flow Chemistry Technology

October 6th, 2009 – Sigma-Aldrich (Nasdaq: SIAL) announced today that it has signed a distribution agreement with ThalesNano, the world leader in bench top flow chemistry instruments, the terms of which will see Sigma-Aldrich distribute ThalesNano’s complete line of approximately 400 CatCart® catalyst products for flow chemistry solutions on a global basis.
ThalesNano flow reactors and CatCart catalyst cartridges provide organic chemists in academic research, large pharmaceutical companies and the chemical and petroleum industries with the means to perform catalytic reactions that are often not possible using traditional batch chemistry processes. Using this technology, chemists can develop new chemicals, or devise faster, better yielding routes and processes to produce existing chemicals.

“Sigma-Aldrich is proud to partner with an innovative company like ThalesNano and to support the next-generation technology of flow chemistry,” said Nigel Mobbs, Sigma-Aldrich Market Segment Manager. “Flow chemistry solutions offer many advantages over traditional methods of performing organic synthesis, delivering better yields and faster reactions, while eliminating many reaction hazards. ThalesNano’s H-Cube®, H-Cube Midi® and X-Cube® flow reactors and CatCart catalyst cartridges give chemists more reactions, with shorter development and scale-up times. Sigma-Aldrich distribution will provide chemists around the world easier access to research and the ability to develop new molecules using these flow reactors and catalysts.”
Dominic Gallello, Executive Co-Chairman at ThalesNano added: “Sigma-Aldrich is a trusted brand recognized around the world. Our goal is to provide our global customers with the availability and rapid delivery of catalysts, critical elements to accelerate the discovery process in a broader range of industries.”

For more information on the complete range of ThalesNano CatCart products offered by Sigma-Aldrich, go to www.sigma-aldrich.com/catcarts.

About Sigma-Aldrich:

Sigma-Aldrich is a leading Life Science and High Technology company. Its biochemical and organic chemical products and kits are used in scientific research, including genomic and proteomic research, biotechnology, pharmaceutical development and as key components in pharmaceutical, diagnostic and other high technology manufacturing. The Company has customers in life science companies, university and government institutions, hospitals, and in industry. Over one million scientists and technologists use its products. Sigma-Aldrich operates in 38 countries and has 7,800 employees providing excellent service worldwide. Sigma-Aldrich is committed to Accelerating Customer Success through Innovation and Leadership in Life Science, High Technology and Service. For more information about Sigma-Aldrich, please visit its award-winning website at http://www.sigma-aldrich.com.

About ThalesNano Inc.:

ThalesNano is the world leader in bench-top flow chemistry reactors. The company has the widest portfolio of continuous process instruments for the pharmaceutical, biotech, fine chemical, petroleum/biofuel and education markets. Its R&D 100 award winning H-Cube® and scale-up system H-Cube Midi® are used in hundreds of laboratories globally and have become the new industry standard for hydrogenation. Within three years from the original introduction of its flagship H-Cube product, 20 out of the top 20 pharmaceutical companies have introduced and adopted the technology.

Contact: Laszlo Urge, Ph.D., CEO, e-mail: ceodirect@thalesnano.com, Telephone: +36-1-880-8500
More information about ThalesNano can be found at www.thalesnano.com

Sigma-Aldrich is a registered trademark of Sigma-Aldrich Biotechnology LP and Sigma-Aldrich Co. CatCart, H-Cube, H-Cube Midi and X-Cube are trademarks of ThalesNano Nanotechnology, Inc.

Donau Lab to Distribute ThalesNano’s Flow Chemistry Reactors in Central Europe and Russia/CIS Countries

October 5th, 2009 – Budapest, Hungary, London, UK, Princeton, US and Zurich, Switzerland – ThalesNano, the world leader in bench top flow chemistry reactors and Donau Lab AG, one of the largest providers of scientific instruments in Eastern Europe and CIS Countries announced today that Donau Lab will distribute ThalesNano’s award winning product line.

“We are very excited about forming a partnership with Donau Lab said Dominic Gallello, Executive Co-Chairman of ThalesNano. “Having an established brand like Donau to sell and support ThalesNano’s product is very important for our customers and potential customers. Donau’s scientific competence will help to insure that users can rapidly achieve great results”.

“We have been representing leading scientific product companies in the region for more than 30 years”, said Peter Gerwig, President of Donau Labs. “We are delighted to add the ThalesNano product line to our solutions offering. Our customers are always interested in being introduced to new technology that will leap them forward in organic synthesis and catalyst development. ThalesNano’s products match this need very well”.

About ThalesNano Inc.
ThalesNano is the world leader in bench-top flow chemistry reactors. The company has the widest portfolio of continuous process instruments for the pharmaceutical, biotech, fine chemical, petroleum/biofuel and education markets. Its R&D 100 award winning H-Cube® and scale-up system H-Cube Midi® are used in hundreds of laboratories globally and have become the new industry standard for hydrogenation. Within three years from the original introduction of its flagship H-Cube product, 20 out of the top 20 pharmaceutical companies have introduced and adopted the technology.
Contact: Laszlo Urge, Ph.D., CEO, e-mail: ceodirect@thalesnano.com, Telephone: +36-1-880-8500

About Donau Lab Group
Donau Lab Group has more than 30 years of tradition and experience in distributing and servicing high quality laboratory equipment. The company has 17 offices and more than 150 employees, covering all 28 countries of Central Europe and Russia/CIS. The portfolio of Donau Lab includes products of global market leaders, producing dedicated instruments for application fields such as synthetic chemistry, biotechnology, microbiology, analytical chemistry and pharmaceutical technology. Donau’s close partnership with its suppliers and the high competence of its employees help to insure customer success.
Contact: Jozsef Papp, Central Product Manager, email: papj@donaulab.com, Telephone: +36-1-319-1718

Former New York Governor George Pataki Joins ThalesNano’s Board of Advisors

September 15th, 2009 – Budapest, Hungary, London, UK, and Princeton, US – ThalesNano Inc., the world leader in bench top flow chemistry reactors announced today the addition of George Pataki, New York Governor, 1995 – 2006, to its Board of Advisors.

“ThalesNano has a long history of global success in the pharmaceutical, biotech, fine chemical and education markets”, said Dr. Ferenc Darvas, Founder and Chairman of ThalesNano. We are now at an inflection point, moving a number of our technologies toward renewable energy. We warmly welcome Governor Pataki’s vast experience in this sector as we navigate the company through the opportunities that could have a long lasting impact on how energy is produced, stored and transported”.

“I have known the company for some time now”, said Governor Pataki. “I have always been amazed with the disruptive innovation that ThalesNano has been able to bring to market. I am delighted to be able to help steer critical parts of this innovation to market needs that I feel so strongly about. We really can make a difference in renewable energy”.

About ThalesNano Inc.

ThalesNano is the world leader in bench-top flow chemistry reactors. The company has the widest portfolio of continuous process instruments for the pharmaceutical, biotech, fine chemical, petroleum/biofuel and education markets. Its R&D 100 award winning H-Cube® and scale-up system H-Cube Midi® are used in hundreds of laboratories globally and have become the new industry standard for hydrogenation. Within three years from the original introduction of its flagship H-Cube product, 20 out of the top 20 pharmaceutical companies have introduced and adopted the technology.

Contact: Laszlo Urge, Ph.D., CEO, e-mail: ceodirect@thalesnano.com, Telephone: +36-1-880-8500

More information about ThalesNano can be found at www.thalesnano.com

MetaProteomics, LLC Acquires State-of-the-Art, Environmentally Friendly Thalesnano H-Cube® Instrument for Use in Phytochemical Research

August 19th, 2009 – Metagenics, Inc. – MetaProteomics, LLC, the biotechnology unit of Metagenics, Inc. announced today that is has acquired a ThalesNano H-Cube instrument. This innovative device utilizes continuous-flow technology to generate in situ hydrogen, a process crucial to phytochemical research for selectively transforming organic compounds in order to study their health-improving properties.

Compared to traditional approaches such as batch flow technology, the H-Cube is faster, less expensive, and usually provides greater yields. The H-Cube is a standalone small bench-top device that produces hydrogen on demand in trace amounts. Hydrogen storage is not required, which results in a much smaller footprint and a more economical use of space. The transformations occur on environmentally friendly, disposable catalyst modeled after larger micro-flow systems.

Brian Carroll, PhD, senior scientist at MetaProteomics said: “We are privileged in joining other world-class research laboratories that are using this innovative technology offered by ThalesNano. This and other flow-techniques enable our natural products scientists to achieve their objectives with less costs and greater sustainability for our environment.”

About Metagenics, Inc.

Metagenics, headquartered in San Clemente, CA, is a global life sciences company focused on reversing chronic illness and improving health. Founded in 1983, the company serves tens of thousands of health care professionals and more than a million patients throughout the world and holds more than 40 proprietary formula patents for use in nutraceuticals, medical foods, and pharmaceuticals. Today, Metagenics continues its leadership role by successfully merging the disciplines of nutritional genomics, functional medicine, and therapeutic lifestyle change programs to find solutions to society’s most pressing health concerns. For more information, please visit http://www.metagenics.com.

About MetaProteomics, LLC

MetaProteomics is focused on discovering and developing proprietary, orally bioavailable, small molecule therapeutics for prevention and treatment of chronic diseases such as type 2 diabetes, cardiometabolic syndrome, vascular diseases, osteoporosis, osteoarthritis, autoimmune inflammatory diseases, and specific cancers. MetaProteomics screens natural molecules with a history of safe use with its ExpresSyn® selective kinase response modulator (SKRM) discovery platform to identify bioactive therapeutics that can be safely used for long-term therapy for chronic disease as drugs or as nutritionals incorporated into therapeutic lifestyle change programs. MetaProteomics rapidly commercializes its proprietary nutritional discoveries as medical foods, nutraceuticals, and OTC drugs while concurrently developing prescription drugs from the most bioactive candidates. MetaProteomics is a subsidiary of Metagenics, Inc.

NET INTERLAB, S.A. to Distribute ThalesNano’s Flow Chemistry Products

July 27th, 2009 – Budapest, Hungary, London, UK, Princeton, US and Madrid, Spain – ThalesNano, the world leader in bench top flow chemistry reactors and NET INTERLAB, S.A., a leading provider of scientific instruments for organic synthesis announced today that NET INTERLAB will distribute ThalesNano’s award winning product line in Spain.

“The market for organic synthesis is growing rapidly in Spain and we were looking for a company that was an expert in this field. NET INTERLAB has a long experience in organic chemistry and in helping companies to be successful, so it was an easy choice”, said Carl Jones, Head of Sales for ThalesNano, Inc.

“Spain has a long tradition of scientific excellence and is emerging as an innovative leader in pharmaceutical and biotechnology”, said F. Moreno – Sales Manager, of NET INTERLAB. “There are over 700 companies engaged in biotechnology alone. ThalesNano’s products offer tremendous advantages, and companies in Spain are already realizing the benefits”.

About ThalesNano Inc.
ThalesNano is the world leader in bench-top flow chemistry reactors. The company has the widest portfolio of continuous process instruments for the pharmaceutical, biotech, fine chemical, petroleum/biofuel and education markets. Its R&D 100 award winning H-Cube® and scale-up system H-Cube Mid™ are used in hundreds of laboratories globally and have become the new industry standard for hydrogenation. Within three years from the original introduction of its flagship H-Cube product, 20 out of the top 20 pharmaceutical companies have introduced and adopted the technology.

Contact: Laszlo Urge, Ph.D., CEO, e-mail: ceodirect@thalesnano.com, Telephone: +36-1-880-8500

ThalesNano Receives the Millennium Award for Intellectual Property Strategy

May 22nd, 2009 – Budapest, Hungary, London, UK, Princeton, US – On April 24 ThalesNano Zrt. was honoured to receive the Millennium Award, established by the Hungarian Patent Office. The Board of Trustees, appointed by the Hungarian Patent Office, awards this accolade to institutions that play an especially important role in the protection of intellectual property.

The award was accepted by Dr. Ferenc Darvas, the Founder & Chairman. “Disruptive innovation in R&D is a integral part of the company’s accomplishments, both in the past and in the future”, said Dr. Darvas. “This award belongs to and recognizes the achivements of the entire research and development community at ThalesNano. Our corporate philosophy is to undertake our research and development with a high level of innovation that solves difficult customer problems. This is a key component in our company’s ability to develop and prosper. An integral component is the appropriate protection of intellectual property. Thanks to ThalesNano’s innovations and patents, we increased our revenue by 50 percent last year. We are very proud that we are an important supplier for nearly all of the major pharmaceutical and chemical companies worldwide including 20 out of the 20 of the world’s largest pharmaceutical companies”.

About ThalesNano Inc.
ThalesNano www.thalesnano.com is a world-leading provider of continuous process chemistry instruments in the rapidly developing market of laboratory and process scale flow reactors. The company has the widest portfolio of bench-top continuous process instruments. Its R&D 100 award winning H-Cube® continuous-flow hydrogenation reactor and the pilot plant scale version H-Cube Mid™ are used in hundreds of laboratories in four continents and have become the new industry standard for hydrogenation.
Contact: Laszlo Urge, Ph.D., CEO, e-mail: ceodirect@thalesnano.com, Telephone: +36-1-880-8500

Discovery of sleeping sickness cure aided by H-Cube®

May 8th, 2009 – A collaboration between groups led by Dr. John Spencer at Greenwich University in the UK and Professor Simon Mackay and Professor Alan Harvey at Strathclyde University in Scotland has led to the discovery of a novel class of benzodiazepines with submicromolar activity against trypanosoma brucei spp., a parasitic species that causes African trypanosomiasis or sleeping sickness in humans.

The work was helped by the use of a H-Cube® continuous-flow hydrogenation reactor used for hydrogenation and developed by ThalesNano, based in Budapest, Hungary.

Dr. John Spencer, Reader in Medicinal Chemistry, said: ‘Rajendra Rathnam, one of my PhD students at Greenwich, has successfully synthesised a number of benzodiazepine containing amines by a variety of reduction methods from their nitro precursors including microwave reductions with Molybdenum hexacarbonyl/DBU or Tin(II) Chloride, but the H-Cube® flow method provided compounds in approximately 5 minutes in high yields and without the need for work-up or column chromatography. Such an approach is very promising for the generation of libraries of bioactive molecules and can expedite drug discovery significantly.’

‘We are proud that our technology can play an important role in advancing science,’ said Richard Jones, Director of Product Management at ThalesNano.

‘From its introduction, H-Cube® has opened up vast new areas of chemistry due to its advantages of speed, selectivity and yield.’