Increasing selectivity of CC chemokine receptor 8 antagonists by engineering nondesolvation related interactions with the intended and off-target binding sites

Shamovsky, I.; de Graaf, C.; Alderin, L.; Bengtsson, M.; Bladh, H.; Börjesson, L.; Connolly, S.; Dyke, H. J.; van den Heuvel, M.; Johansson, H.; Josefsson, B.; Kristoffersson, A.; Linnanen, T.; Lisius, A.; Mannikko, R.; Norden, B.; Price, S.; Ripa, L.; Rognan, D.; Rosendahl, A.; Skrinjar, M.; Urbahns, K.; J. Med. Chem., 2009, 52, 7706-7723

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