Collaboration on Flow Chemistry Technologies

ThalesNano Inc. and the Christian Doppler Laboratory for Microwave Chemistry in Graz, Austria Collaborate on Flow Chemistry Technologies

Budapest/Graz, 19th November, 2007. ThalesNano Inc. and the Christian Doppler Laboratory for Microwave Chemistry (CDLMC) located at Karl-Franzens-University in Graz today announced a scientific collaboration on flow/microwave chemistry research. The project will focus on the application of flow reactors for organic synthesis and the development of novel technologies utilizing ThalesNano’s background in continuous processing. ThalesNano and the Christian Doppler Research Association (CDG) will jointly provide financial support for the collaboration.

Dr. Laszlo Urge, CEO of ThalesNano Inc, said “We joined forces with one of the leading research laboratories in Europe for the application of our technologies. This will enable us to jointly develop novel methods and environmentally friendly solutions with our technology. The Christian Doppler Research Association in Austria provides a great example on how to effectively support basic and applied research and innovation. The Christian Doppler Laboratory for Microwave Chemistry under the leadership of Professor C. Oliver Kappe has proven over the last several years how the adaptation of new technologies can impact the development of science and technology in the field of chemistry. We expect that the collaboration results in further innovations.”

Professor Kappe, the Director of the CDLMC, commented “We believe that this collaboration with ThalesNano, one of the leading companies involved in flow chemistry instrument and application development will result in the creation of further important technologies, from which the entire chemistry community in both academia and industry could benefit from.

Professor Ferenc Darvas, president and chairman of ThalesNano Inc. said: “This agreement emphasizes that collaborations between academia and industry are essential and can create economically viable results. The Christian Doppler Laboratory for Microwave Chemistry is leading scientific application development and contributed significantly to the general acceptance of microwave technologies so far.”

For more information please go to: www.thalesnano.com

About ThalesNano Inc.

ThalesNano is a world-leading provider of flow chemistry instruments for laboratories with well over 50 % share on the explosively developing market of laboratory flow reactors. Its H-CubeTM , continuous-flow hydrogenation reactors with no outside hydrogen gas source (also available for scale up), has been used in hundreds of labs in four continents. After being awarded as one of the 100 most technologically significant and innovative new products of 2005 by the R&D Magazine, ThalesNano this year successfully generalized the concept of H-Cube by creating and bringing to the market the X-Cube, a high-pressure, high-temperature general purpose flow reactor for liquid or liquid/gas phase reactions. Apart from instrument development, ThalesNano provides synthetic and scale-up solutions to the industry, together with training and technical support.

Flow chemistry, an emerging technology allows the highly effective and rapid synthesis of organic compounds, in particular under hitherto unrealizable hazardous reaction conditions. Additional benefits are seen in the area of green chemistry and lab automation. This technology furthermore promotes the rapid scale-up from mg to kg quantities with quick turnover, high quality stabilization, and reduced footprint leading to minimized CAPEX and OPEX

Contact: Dr. Laszlo Urge CEO, Tel: +36 1 8808 500, or send an email to info@thalesnano.com

About Christian Doppler Research Association

The Austrian Christian Doppler Research Association (CDG) is a non-profit association that aims at promoting application oriented basic research in the areas of natural sciences, technology and economy. It enables talented scientists in renowned research centers to achieve high-quality research and knowledge transfer in line with the demands and to the advantage of the CDG member companies. The CD Labs are jointly funded by the Austrian Federal Ministry of Economics and Labour and the Austrian National Foundation for Research, Technology and Development as well as by contributions from the cooperating members (www.cdg.ac.at). The Christian Doppler Laboratory for Microwave Chemistry (CDLMC) was established in 2006 and performs basic and applied research on microwave chemistry in collaboration with industrial partners (www.maos.net)

ThalesNano and ETH Zurich collaborate on Flow Chemistry Technologies

Budapest/Zurich, October 25, 2007. ThalesNano Inc. and ETH Zurich, ThalesNano today announced collaboration with the Swiss Federal Institute of Technology Zurich (ETH Zurich) on flow chemistry applications. The agreement will focus on the application of chemistries and technologies utilizing ThalesNano’s products to solve difficult chemistry applications.

Dr. Laszlo Urge, CEO of ThalesNano Inc., said “We are extremely pleased to be able to collaborate with one of the top research universities in the world. This collaboration will enable us to utilize our technology and to jointly develop novel applications that will serve the entire scientific community. Our products are in use at all major pharmaceutical, agrochemical and chemistry companies and also support in-house scientists in developing their own novel applications. The technology developed as part of this collaboration may result in spin-off opportunities in future.”

Professor Peter Seeberger whose laboratory at ETH Zurich is leading the project said “We are delighted to have this collaboration with the foremost company in flow chemistry instrument and application development. This is a very exciting area of technology, and in it we anticipate being able to contribute to the development of novel chemistries. There are a lot of scientific and technical advantages in this field. We are looking forward to the combined exploration. ”

Professor Ferenc Darvas, president and chairman of ThalesNano Inc. said: “This agreement again highlights the interest that the academic world has shown in using our products, such as H-Cube, H-Cube Tutor and X-Cube, to develop applications. ETH Zurich and other leading universities are proactive, taking the lead in application development. Our work with ETH Zurich underscores that academic collaboration with industry is key to the full implementation and utilization of novel technologies.

For more information please go to: www.thalesnano.com
About ThalesNano Inc.

ThalesNano is a technology-intensive company that provides solutions for leading pharmaceutical and biotechnology companies all over the world. It specializes in developing and providing microscale flow instruments for chemistry by exploiting the benefits of combining microfluidics, mezofluidics or nanotechnology with flow chemistry.

R&D Magazine recognized the award winning development, H-CubeTM, as one of the 100 most technologically significant and innovative new products of 2005. H-CubeTM is the first in a new wave of continuous-flow hydrogenation reactors. Utilizing water electrolysis to generate hydrogen, a catalyst cartridge system and a continuous-flow reactor, the shoe-box sized H-CubeTM makes hydrogenation convenient, more efficient and less hazardous. X-Cube is a high-pressure, high-temperature flow reactor. With these tools, reactions that are almost impossible to carry out under normal circumstances can be safely performed. .

Contact: Dr. Laszlo Urge CEO, Tel: +36 1 8808 500, or send an email to info@thalesnano.com
About ETH Zurich

ETH Zurich (Swiss Federal Institute of Technology) has a student body of over 13,000 students from 80 nations. Nearly 360 professors teach mainly in engineering sciences and architecture, system-oriented sciences, mathematics and natural sciences, as well as carry out research that is highly valued worldwide. Distinguished by the successes of 21 Nobel laureates, ETH Zurich is committed to providing its students with unparalleled education and outstanding leadership skills.

ThalesNano Announces The Launch Of H-Cube Mid™

ThalesNano announces the launch of H-Cube Midi®, its next generation hydrogenation technology product applicable for process development

Budapest Hungary, Princeton New Jersey and London, UK October 8, 2007. ThalesNano Inc. announced today that it has launched the latest of its Cube® flow reactor series, H-Cube Midi®. . This novel product is now commercially available and validated with several important chemistry applications.

The H-Cube Midi® is designed to fulfill the requirements of process scale flow hydrogenation. Based upon the current H-Cube® technology platform, the H-Cube Midi® is designed to increase the capacity of the present H-Cube® up to kg quantities per day without compromising efficiency and safety.

Dr. Laszlo Urge, CEO of ThalesNano commented: “H-Cube Midi® was designed in response to increasing customer needs to be able to scale up reactions optimized on H-Cube®. Several pharmaceutical companies have adopted H-Cube® as the first choice for hydrogenation in discovery. As compounds move from discovery to development, there is a need to increase the scale up to kg levels as fast as possible. The H-Cube Midi® allows the optimization and transition from mg scale to kg levels to be performed within a day. The increase in productivity and the savings in cost and time are expected to be significant for those R&D organizations who have adopted this technology.”
“The launch of this new product underlines that we are executing a complex strategy and building a product portfolio in the flow chemistry area. Our product development strategy is designed to provide integrated continuous flow solutions from discovery to full scale production and could help solve some of the bottlenecks in the pharmaceutical and chemical industries” stated Dr. Ferenc Darvas, President and Chairman at ThalesNano.

For more information please refer to ThalesNano’s website at www.thalesnano.com

About ThalesNano:

ThalesNano is a technology-intensive company that provides chemical solutions in discovery, process development and production for pharmaceutical and chemical companies. The Company specializes in developing and providing microscale flow instruments for chemistry, by exploiting the benefits of combining micro- and meso-fluidics and nanotechnology with flow chemistry.

The award winning development, H-Cube®, has been recognized as one of the 100 most technologically significant and innovative new products of 2005 by R&D Magazine and is the first in a new wave of continuous-flow hydrogenation reactors. Utilizing water electrolysis to generate hydrogen, with a catalyst cartridge system and with a continuous-flow reactor, the shoe-box sized H-Cube® makes hydrogenation convenient, more efficient and less hazardous. With this equipment, reactions that are extremely challenging to carry out with traditional methods can be performed. These products are already on the market and utilized by 18 of the top 20 pharmaceutical companies in the world.

Contact: Laszlo Urge CEO, e-mail: titkarsag@thalesnano.com, Telephone: +36-1-880-8500

ThalesNano Inc. opens own representation in the United Kingdom and has new distribution agreements for Europe and India

Budapest, Hungary: September 24th, 2007. ThalesNano Inc., a leading developer and manufacturer of flow chemistry, flow reactor technology, and hydrogenation technology solutions, announced today that it had continued to expand globally by opening a subsidiary in the United Kingdom and by signing distributor agreements in Scandinavia, Italy, and India.

Building its own subsidiary reflects ThalesNano’s commitment to bridging closer ties with its customers and expanding operations globally; it is intended to enhance activities in particular towards the chemical and pharmaceutical sectors, and to reinforce visibility. The UK representatives will bring both added value in operational terms and flexibility for customers.

Alex Drijver, CFO commented: “Chemists will have a local point of contact for advice on the most up-to-date chemistry technologies and solutions. ThalesNano Inc. was already operating successfully through a distributor company in the UK and can now strengthen and consolidate its position with help of its local team of professionals. The UK is a strategic market for the company’s growth, as the country’s R&D spending is the largest within Europe and has the most developed and innovative pharmaceutical and chemical industry. In this way, ThalesNano Inc. can effectively support UK customers at all times with the necessary technology knowledge.”

The new UK ThalesNano team replaces former distributor Asynt Inc., with whom the company’s contract expired in September. The Danish distributor company, Biolab A/S is taking over customers from Asynt Inc. in the Scandinavian region. While in Italy, Stepbio S.R.L. is the new distributor of ThalesNano products.

As a result of ThalesNano’s global expansion, and as a response to the demand for its products and technologies from India, the company has started its operation through cooperation with Inkarp Instruments Pvt. Ltd.

Dr. Ferenc Darvas, president and chairman commented: „The development and growth of both ThalesNano’s sales team and the distributor network comes two years after the initial launch of the award winning H-Cube®, which is rapidly becoming the standard for performing hydrogenation reactions in research laboratories.”

For more information please visit www.thalesnano.com

About ThalesNano Inc.:
ThalesNano Inc. is a technology-intensive company that provides solutions for leading pharmaceutical and biotechnology companies from all over the world. It is specialized in developing and providing microscale flow instruments for chemistry, by exploiting the benefits of combining microfluidics, mezofluidics or nanotechnology with flow chemistry.
The award winning development, H-Cube®, has been recognized as one of the 100 most technologically significant and innovative new products of 2005 by R&D Magazine is the first in a new wave of continuous-flow hydrogenation reactors.

Contact: Dr. Laszlo Urge, CEO e-mail: sales@thalesnano.com, Carl Jones: e-mail: flowchemistry@thalesnano.com

ThalesNano Announces the Launch of H-Cube Tutor™

THALESNANO ANNOUNCES THE LAUNCH OF H-CUBE TUTOR®- A SIMPLE AND SAFE REACTOR TO ENABLE UNDERGRADUATES AND RESEARCHERS TO PERFORM HYDROGENATION AS PART OF THEIR DEGREE

Budapest Hungary June 7, 2007 ThalesNano Nanotechnology Inc., announced today that it has launched the latest of its CubeTM flow reactor series, H-Cube® Tutor which is now commercially available for educational purposes.

Following the H-Cube® and X-Cube® reactors, ThalesNano is proud to present the release of the latest in the flow reactor series, the H-Cube Tutor® hydrogenation reactor. The H-Cube Tutor® is the education oriented version of the original R&D Top 100 award winning hydrogenation reactor, the H-Cube®, and shares the following advantages and features: ELEVATED SAFETY, no hydrogen cylinders necessary (hydrogen is generated from water electrolysis). No catalyst filtering, weighing out, or clean up (catalysts are packed into disposable cartridges), and it can handle reaction temperatures up to 100 Co. It is easy and user friendly to operate, chemists at all level can learn how to use it in minutes.

Dr. Ferenc Darvas, President and Chairman at ThalesNano said: “Undergraduate chemists at many universities are not allowed to practice hydrogenation during their practical session, due to safety concerns with handling hydrogen cylinders and pyrophoric catalysts. It is essential for their future industrial or academic career to gain first hand practical experience with hydrogenation during their educational years, since approximately 5-10% of reactions in the whole of the chemical industry are a kind of hydrogenation.”

Dr. Laszlo Urge, CEO commented “With the launch of this new product ThalesNano have a diversified product portfolio that covers a wide market segment for the flow chemistry applications of laboratory scale synthesis from the academic to the industrial.”

For more information please refer to ThalesNano’s website at www.thalesnano.com

About ThalesNano:
ThalesNano is a technology-intensive company that provides solutions for leading pharmaceutical and biotechnology companies from all over the world. It is specialized in developing and providing microscale flow instruments for chemistry, by exploiting the benefits of combining microfluidics, mezofluidics or nanotechnology with flow chemistry.

The award winning development, H-Cube®, has been recognized as one of the 100 most technologically significant and innovative new products of 2005 by R&D Magazine is the first in a new wave of continuous-flow hydrogenation reactors. Utilizing water electrolysis to generate hydrogen, with a catalyst cartridge system and with a continuous-flow reactor, the shoe-box sized H-Cube® makes hydrogenation convenient, more efficient and less hazardous. With this equipment, reactions that are almost impossible to carry out under normal circumstances can be performed. The product is already on the market.

Contact: Laszlo Urge CEO e-mail: sales@thalesnano.com

ThalesNano Announces the Launch of New Products for Enantio-selective and Stereo-selective Catalytic Hydrogenations

THALESNANO ANNOUNCES THE LAUNCH OF NEW PRODUCTS FOR ITS H-CUBE® FOR
ENANTIO-SELECTIVE AND STEREO-SELECTIVE CATALYTIC HYDROGENATIONS

March 20, 2007, Budapest, Hungary – ThalesNano Inc., announced today that it has validated and launched new products and applications for its H-CubeTM bench-top catalytic hydrogenator. H- Cube was recognized as one of the 100 most technologically significant and innovative new products of 2005 by R&D Magazine The new series of CatCartsTM, ThalesNano’s unique catalyst cartridge system for use in its flow reactors, filled with immobilized catalysts will enable scientists to carry out enantio-selective and stereo-selective catalytic hydrogenations while working with the H-CubeTM. These products will be launched at the American Chemical Society’s 233rd National Meeting & Exposition, March 25-29, 2007, in Chicago, IL USA. (for more information visit: www.acs.org)

Catalytic hydrogenation is one of the cleanest chemical transformations; however its safe handling has so far required expensive and special dedicated facilities. ThalesNano’s H-CubeTM hydrogenation bench top reactor can perform these transformations safely in standard laboratories even at high pressure and temperature. As a result of the extension of the application area, chemists will be able to perform otherwise complicated enantio-selective hydrogenation reactions in H-CubeTM routinely.

Laszlo Urge, CEO of International Operations said: “These new products will widen the application area of the H-CubeTM hydrogenation reactor significantly. Enantio-selective hydrogenation represents an important transformation in the search for novel biologically active compounds, and is a bottleneck in many of the pharmaceutical industrial processes. It also requires a special infrastructure that makes it less appealing for discovery chemistry. The importance of enantio-selective hydrogenations is underlined by the fact that scientists who were pioneering this field were awarded the Nobel Prize in 2001 for their achievements.

An ever increasing number of chemists throughout the pharmaceutical and biotech industry are utilizing ThalesNano’s revolutionary H-CubeTM, that makes catalytic hydrogenation in laboratories significantly more effective than traditional methods. It also allows easy automation even at high temperature and pressure. This enables chemists to carry out catalyst screening and quick process optimization while scanning a wide parameter range. As a result a large number of discovery protocols are currently created and they will be transferred to development and scale up for the production of clinical materials. Due to the relatively easy scale up with ThalesNano flow reactors, the time required to transfer results from discovery to development could be shortened. Therefore we foresee great potential for entering process chemistry downstream from discovery with this new product family soon. ”

Dr. Ferenc Darvas, President and Chairman at ThalesNano commented “These products have great potential and will make the work of chemists more effective. We are finding more and more applications that cannot be solved with traditional methods. It also underlines that ThalesNano is executing a strategy, where we could provide novel solutions not only for the discovery and for the development phases of the pharmaceutical industry, but for the petrochemical, food and cosmetics industry as well. These integrated solutions could effect both discovery and development and could help solve some of the bottlenecks in the R&D areas.”

For more information please refer to ThalesNano’s website at www.thalesnano.com

About ThalesNano:

ThalesNano is a technology-intensive company that provides solutions for leading pharmaceutical and biotechnology companies from all over the world. It is specialized in developing and providing microscale flow instruments for chemistry, by exploiting the benefits of combining microfluidics, mezofluidics or nanotechnology with flow chemistry.

The award winning development, H-CubeTM, has been recognized as one of the 100 most technologically significant and innovative new products of 2005 by R&D Magazine is the first in a new wave of continuous-flow hydrogenation reactors. Utilizing water electrolysis to generate hydrogen, with a catalyst cartridge system and with a continuous-flow reactor, the shoe-box sized H-CubeTM makes hydrogenation convenient, more efficient and less hazardous. With this equipment, reactions that are almost impossible to carry out under normal circumstances can be performed. The product is already on the market and Thales Nanotechnology expects that its unique development will revolutionize catalytic hydrogenation in the next decade.

Contact: Dr. László Ürge, CEO e-mail: titkarsag@thalesnano.com