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Life cycle analysis within pharmaceutical process optimization and intensification: case study of active pharmaceutical ingredient production
Ott, D.; Kralisch, D.; Dencic, I.; Hessel, V.; Laribi, Y.; Perrichon, P. D.; Berguerand, C.; Kiwi-Minsker, L.; Loeb, P.; ChemSusChem, 2014, 7, 3521-3533
Aerobic flow oxidation of alcohols in water catalyzed by platinum nanoparticles dispersed in an amphiphilic polymer
Osako, T.; Torii, K.; Uozumi, Y.; RSC Adv., 2015, 5, 2647-2654
Chemical assembly systems: Layered control for divergent, continuous, multistep syntheses of active pharmaceutical ingredients
Ghislieri, D.; Gilmore, K.; Seeberger, P. H.; Angew. Chem. Int. Ed., 2014, 54(2), 678-682
Total synthesis of the macrocyclic N-methyl enamides palmyrolide A and 2S-sanctolide A
Wadsworth, A. D.; Furkert, D. P.; Brimble, M. A.; J. Org. Chem., 2014, 79(22), 11179-11193
Novel derivatives of usnic acid effectively inhibiting reproduction of influenza A virus
Shtro, A. A.; Zarubaev, V. V.; Luzina, O. A.; Sokolov, D. N.; Kiselev, O. I.; Salakhutdinov, N. F.; Bioorg. Med. Chem., 2014, 22(24), 6826-6836
Discovery of dual leucine zipper kinase (DLK, MAP3K12) inhibitors with activity in neurodegeneration models
Patel, S.; Cohen, F.; Dean, B. J.; De La Torre, K.; Deshmukh, G.; Estrada, A. A.; Ghosh, A. S.; Gibbons, P.; Gustafson, A.; Huestis, M. P.; Le Pichon, C. E.; Lin, H.; Liu, W.; Liu, X.; Liu, Y.; Ly, C. Q.; Lyssikatos, J. P.; Ma, C.; Scearce-Levie, K.; Shin, Y. G.; Solanoy, H.; Stark, K. L.; Wang, J.; Wang, B:; Zhao, X.; Lewcock, J. W.; Siu, M.; J. Med. Chem., 2015, 58(1), 401-418
Total synthesis of aignopsanes, a class of sesquiterpenes: (+)‐Aignopsanoic acid A, (−)‐methyl aignopsanoate A, and (−)‐isoaignopsanoic A
Burki, C.; Bonjoch, J.; Bradshaw, B.; Villa, G.; Renaud, P.; Chem. Eur. J., 2015, 21(1), 395-401
Expanding the utility of flow hydrogenation – a robust protocol restricting hydrodehalogenation
Hizartzidis, L.; Cossar, P. J.; Robertson, M. J.; Simone, M. I.; Young, K. A.; McCluskey, A.; Gordon, C. P.; RSC Adv., 2014, 4, 56743-56748
Concise synthesis of vesnarinone and its analogues by using Pd‐catalyzed C–N bond‐forming reactions
See, Y. Y.; Dang, T. T.; Chen, A.; Seayad, A. M.; Eur. J. Org. Chem., 2014, 7405-7412